introduction to bioinformatics

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Introduction To Bioinformatics

Author : Stephen A. Krawetz
ISBN : 1588290646
Genre : Computers
File Size : 57. 66 MB
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A comprehensible introduction to the key biological, mathematical, statistical, and computer concepts and tools behind bioinformatics. For physical scientists, the book provides a sound biological framework for understanding the questions a life scientist would ask in the context of currently available computational tools. For life scientists, a complete discussion of the UNIX operating system offers biologists graphical-user-interface comfort in a command-line environment, plus an understanding of the installation and management of UNIX-based software tools. In the applications sections the book provides a common meeting ground for life and physical scientists. Here they will find examples of the management and analysis of DNA sequencing projects, the modeling of DNA as a statistical series of patterns, various methods of pattern discovery, protein visualization, and the use of multiple sequence alignment to infer both functional and structural biological relationships. An accompanying CD contains several full and limited trial-versions of the programs discussed in the text, as well as a complete set of illustrations from each chapter suitable for lectures and presentations.

Introduction To Bioinformatics

Author : Anna Tramontano
ISBN : 9781351989411
Genre : Science
File Size : 33. 16 MB
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Guiding readers from the elucidation and analysis of a genomic sequence to the prediction of a protein structure and the identification of the molecular function, Introduction to Bioinformatics describes the rationale and limitations of the bioinformatics methods and tools that can help solve biological problems. Requiring only a limited mathematical and statistical background, the book shows how to efficiently apply these approaches to biological data and evaluate the resulting information. The author, an expert bioinformatics researcher, first addresses the ways of storing and retrieving the enormous amount of biological data produced every day and the methods of decrypting the information encoded by a genome. She then covers the tools that can detect and exploit the evolutionary and functional relationships among biological elements. Subsequent chapters illustrate how to predict the three-dimensional structure of a protein. The book concludes with a discussion of the future of bioinformatics. Even though the future will undoubtedly offer new tools for tackling problems, most of the fundamental aspects of bioinformatics will not change. This resource provides the essential information to understand bioinformatics methods, ultimately facilitating in the solution of biological problems.

Introduction To Bioinformatics

Author : Teresa K. Attwood
ISBN : STANFORD:36105110143414
Genre : Science
File Size : 65. 92 MB
Format : PDF, Kindle
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Bioinformatics, the application of computers in biological sciences and especially analysis of biological sequence data, is becoming an essential tool in molecular biology as genome projects generate vast quantities of data. This text provides an introduction to the subject for undergraduates (final year), focussing on two key areas, genojmics and protein sequence analysis. It provides an overview of primary, composite and secondary databases, and gives a brief introduction to the Internet and the World Wide Web.

An Introduction To Bioinformatics Algorithms

Author : Neil C. Jones
ISBN : 0262101068
Genre : Computers
File Size : 23. 15 MB
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Algorithms and Complexity. Molecular Biology Primer. Exhaustive Search. Greedy Algorithms. Dynamic Programming Algorithms. Divide-and-Conquer Algorithms. Graph Algorithms. Combinatorial Pattern Matching. Clustering and Trees. Hidden Markov Models. Randomized Algorithms.

Introduction To Bioinformatics

Author : Arthur Lesk
ISBN : 9780199651566
Genre : Science
File Size : 64. 21 MB
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Lesk provides an accessible and thorough introduction to a subject which is becoming a fundamental part of biological science today. The text generates an understanding of the biological background of bioinformatics.

Introduction To Bioinformatics

Author : Arthur M. Lesk
ISBN : 0199251967
Genre : Computers
File Size : 57. 86 MB
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Bioinformatics is the collective name for a set of skills that has now become arguably one of the most important information-gathering and knowledge-building tools in current science research. The increase in the reliance upon bioinformatics in current research has made it essential fortraining in these skills to become an integral part of current science education. Introduction to Bioinformatics is a timely and much-needed textbook which provides an accessible and thorough introduction to a subject which is becoming a fundamental part of biological science today.As a pioneer of the use of bioinformatics techniques in research, Dr Lesk brings unrivalled experience and expertise to the study of this field. The aim of the book is to generate an understanding of the biological background of bioinformatics, and to integrate this with an introduction to the useof computational skills. Without describing computer science or sophisticated programming skills in detail, the book supports and encourages the application of the many powerful computational tools of bioinformatics in a way that is both relevant to and stimulating for the reader.The book contains numerous problems and innovative Weblems (for Web-based Problems) to encourage students to engage with the subject and, with the accompanying web site, to develop a working understanding and appreciation of the power of bioinformatics as a research tool.Web site www.oup.co.uk/best.textbooks/biochemistry/bioinf/A logo in the text alerts the reader to check the web site for the full text of programs referred to in the book. The web site also has links related to the book's problems, the innovative Weblems (for Web-based Problems), to encourage students to engage with the subject and, with the web site, to develop a working understanding and appreciation of the power of bioinformatics as a research tool.

Text Book Of Bioinformatics

Author : Vinay Sharma
ISBN : 8171339174
Genre : Bioinformatics
File Size : 78. 29 MB
Format : PDF
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1. Introduction to Bioinformatics 2. Introduction to Computers 3. Introduction to Internet 4. Search Engines: Tools for Web Search 5. Programming Languages 6. Genomics and Proteomics 7. Biological Databases 8. Sequence Analysis 9. Phylogenetic Analysis 10. Microarray Technology: A Boon to Biological Sciences 11. Bioinformatic..s in Drug Discovery: A Brief Overview 12. Genome Sequencing Projects 13. BTIS Network In India Index

Algorithms In Bioinformatics

Author : Wing-Kin Sung
ISBN : 1420070347
Genre : Science
File Size : 77. 68 MB
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Thoroughly Describes Biological Applications, Computational Problems, and Various Algorithmic Solutions Developed from the author’s own teaching material, Algorithms in Bioinformatics: A Practical Introduction provides an in-depth introduction to the algorithmic techniques applied in bioinformatics. For each topic, the author clearly details the biological motivation and precisely defines the corresponding computational problems. He also includes detailed examples to illustrate each algorithm and end-of-chapter exercises for students to familiarize themselves with the topics. Supplementary material is available at http://www.comp.nus.edu.sg/~ksung/algo_in_bioinfo/ This classroom-tested textbook begins with basic molecular biology concepts. It then describes ways to measure sequence similarity, presents simple applications of the suffix tree, and discusses the problem of searching sequence databases. After introducing methods for aligning multiple biological sequences and genomes, the text explores applications of the phylogenetic tree, methods for comparing phylogenetic trees, the problem of genome rearrangement, and the problem of motif finding. It also covers methods for predicting the secondary structure of RNA and for reconstructing the peptide sequence using mass spectrometry. The final chapter examines the computational problem related to population genetics.

Introduction To Mathematical Methods In Bioinformatics

Author : Alexander Isaev
ISBN : 3540219730
Genre : Science
File Size : 88. 11 MB
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This book looks at the mathematical foundations of the models currently in use. All existing books on bioinformatics are software-orientated and they concentrate on computer implementations of mathematical models of biology. This book is unique in the sense that it looks at the mathematical foundations of the models, which are crucial for correct interpretation of the outputs of the models.

Bioinformatics Biocomputing And Perl

Author : Michael Moorhouse
ISBN : 9780470026458
Genre : Medical
File Size : 83. 98 MB
Format : PDF
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Bioinformatics, Biocomputing and Perl presents a modern introduction to bioinformatics computing skills and practice. Structuring its presentation around four main areas of study, this book covers the skills vital to the day-to-day activities of today’s bioinformatician. Each chapter contains a series of maxims designed to highlight key points and there are exercises to supplement and cement the introduced material. Working with Perl presents an extended tutorial introduction to programming through Perl, the premier programming technology of the bioinformatics community. Even though no previous programming experience is assumed, completing the tutorial equips the reader with the ability to produce powerful custom programs with ease. Working with Data applies the programming skills acquired to processing a variety of bioinformatics data. In addition to advice on working with important data stores such as the Protein DataBank, SWISS-PROT, EMBL and the GenBank, considerable discussion is devoted to using bioinformatics data to populate relational database systems. The popular MySQL database is used in all examples. Working with the Web presents a discussion of the Web-based technologies that allow the bioinformatics researcher to publish both data and applications on the Internet. Working with Applications shifts gear from creating custom programs to using them. The tools described include Clustal-W, EMBOSS, STRIDE, BLAST and Xmgrace. An introduction to the important Bioperl Project concludes this chapter and rounds off the book.

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