measuring immunity basic science and clinical practice

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Measuring Immunity

Author : Michael T. Lotze
ISBN : 0080479332
Genre : Medical
File Size : 70. 74 MB
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Most of the diseases of modern mankind involve either acute or chronic inflammation. Measuring Immunity integrates the current information available on biomarkers and surrogate assays into a single handbook. It highlights the principles behind various applications, gives a brief summary on how they are conducted and provides detailed and critical analyses of murine models of immunity, clinical trials, and tests to predict utility and benefit. Measuring Immunity is indispensable for scientists and clinicians interested in the clinical applications of modern immunobiology. * Defines which assays of immune function are helpful in the assessment of clinical disorders involving inflammation and immunity * Assesses the dynamics of cellular and soluble factors in the peripheral blood using modern techniques * Includes basic science foundations as well as the approaches currently applied

Encyclopedia Of Analytical Science

Author :
ISBN : 9780081019849
Genre : Science
File Size : 44. 51 MB
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The third edition of the Encyclopedia of Analytical Science is a definitive collection of articles covering the latest technologies in application areas such as medicine, environmental science, food science and geology. Meticulously organized, clearly written and fully interdisciplinary, the Encyclopedia of Analytical Science provides foundational knowledge across the scope of modern analytical chemistry, linking fundamental topics with the latest methodologies. Articles will cover three broad areas: analytical techniques (e.g., mass spectrometry, liquid chromatography, atomic spectrometry); areas of application (e.g., forensic, environmental and clinical); and analytes (e.g., arsenic, nucleic acids and polycyclic aromatic hydrocarbons), providing a one-stop resource for analytical scientists. Offers readers a one-stop resource with access to information across the entire scope of modern analytical science Presents articles split into three broad areas: analytical techniques, areas of application and and analytes, creating an ideal resource for students, researchers and professionals Provides concise and accessible information that is ideal for non-specialists and readers from undergraduate levels and higher

Handbook Of Anticancer Pharmacokinetics And Pharmacodynamics

Author : Michelle A. Rudek
ISBN : 9781461491354
Genre : Medical
File Size : 21. 43 MB
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There are many steps on the road from discovery of an anticancer drug to securing its final approval by the Food and Drug Administration. In this thoroughly updated and expanded second edition of the Handbook of Anticancer Pharmacokinetics and Pharmacodynamics, leading investigators synthesize an invaluable overview of the experimental and clinical processes of anticancer drug development, creating a single indispensable reference that covers all the steps from the identification of cancer-specific molecular targets to screening techniques and the development and validation of bioanalytical methods to clinical trial design and all phases of clinical trials. The authors have included new material on phase 0 trials in oncology, organ dysfunction trials, drug formulations and their impact on anticancer drug PK/PD including strategies to improve drug delivery, pharmacogenomics and cancer therapy, high throughput platforms in drug metabolism and transport pharmacogenetics, imaging in drug development and nanotechnology in cancer. Authoritative and up-to-date, Handbook of Anticancer Pharmacokinetics and Pharmacodynamics, 2nd Edition provides in one comprehensive and highly practical volume a detailed step-by-step guide to the successful design and approval of anticancer drugs. Road map to anticancer drug development from discovery to NDA submission Discussion of molecular targets and preclinical screening Development and validation of bioanalytical methods Chapters on clinical trial design and phase 0, I, II, III clinical trials Pharmacokinetics, pharmacodynamics, pharmacogenomics, and pharmacogenetics of anticancer agents Review of the drug development process from both laboratory and clinical perspectives New technological advances in imaging, high throughput platforms, and nanotechnology in anticancer drug development

An Introduction To Biomedical Science In Professional And Clinical Practice

Author : Sarah Jane Pitt
ISBN : 9781118687710
Genre : Science
File Size : 55. 35 MB
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Biomedical Science in Professional and Clinical Practice isessential reading for all trainee biomedical scientists looking foran introduction to the biomedical science profession whether theyare undergraduates following an accredited biomedical sciences BSc,graduate trainees or experienced staff with overseasqualifications. This book guides trainees through the subjects,which they need to understand to meet the standards required by theHealth Professions Council for state registration. These includeprofessional topics, laws and guidelines governing clinicalpathology, basic laboratory techniques and an overview of eachpathology discipline. It helps trainees at any stage of trainingand in any pathology discipline(s) to think creatively about how togather evidence of their understanding and professional competence.By referring to specialist sources of information in each area, ithelps students to explore particular topics in more depth and tokeep up to date with professional and legalchanges. It is also of value to any Training Officers whoare looking for ideas while planning a programme of training for atrainee biomedical scientist. The book includes basic principles of working in the pathologylaboratory including laws and regulations, which must be observed,such as health and safety, data protection and equal opportunitieslaws and guidelines. Practical exercises are included throughoutthe book with examples of coursework, suggestions for furtherexercises and self -assessment. Summary boxes of key facts areclearly set out in each chapter and ideas for group/tutorialdiscussions are also provided to enhance studentunderstanding.

Annual Report

Author :
ISBN : OSU:32436011255732
Genre : Surgery
File Size : 90. 89 MB
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Hyperthermic Oncology From Bench To Bedside

Author : Satoshi Kokura
ISBN : 9789811007194
Genre : Medical
File Size : 26. 20 MB
Format : PDF, Kindle
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This comprehensive work broadens readers' understanding of the rudimentary mechanism of the anti-cancer effect of hyperthermia. It also presents state-of-the-art clinical outcomes by hyperthermia treatment of cancer. In the past few decades, basic and clinical research have shown through in vitro experiments that hyperthermia inhibits epithelial-mesenchymal transition (EMT), resulting in the prevention of metastasis. It also has been learned that hyperthermia shows its superior benefit when applied in combination with radiation therapy, chemotherapy, or various immunotherapies as treatments of several types of carcinoma. The chapters here from expert contributors describe the details of their research for each type of cancer. This book provides not only an overview and the current status of hyperthermia but also its future perspectives. Therefore this volume will greatly benefit oncologists, radiologists and radiology technologists, and chemotherapists who are involved in immunotherapy for all kinds of cancer.

Research Projects In Dry Eye Syndrome

Author : Horst Brewitt
ISBN : 9783805594189
Genre : Medical
File Size : 67. 91 MB
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Dry eye is one of the most common disorders encountered in ophthalmological practice. Its symptoms cause considerable discomfort and substantially reduce the patient's quality of life. As it is a complex and multifactorial condition, research investigating dry eye is a matter of great interest all over the world. In this book, the wide range of current basic and clinical research in dry eye and correlated ocular surface diseases is presented by scientists from Germany, Austria and the USA. These renowned authors provide clear and extensive descriptions of their projects, enabling scientists and clinical ophthalmologists to quickly bring themselves up to date with cutting edge research in this field. This overview of research into the pathogenesis and clinical treatment of dry eye is a must for all ophthalmologists dealing with this syndrome and looking to increase their knowledge base.

Surgery

Author : Jeffrey Norton
ISBN : 0387681132
Genre : Medical
File Size : 47. 91 MB
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Much anticipated, the Second Edition of Surgery: Basic Science and Clinical Evidence features fully revised and updated information on the evidence-based practice of surgery, including significant new sections on trauma and critical care and the often challenging surgical care of unique populations, including elderly, pediatric, immunocompromised, and obese patients as well as timely new chapters on the pre- and post-operative care of the cardiac surgery patient, intestinal transplantation, surgical infections, the fundamentals of cancer genetics and proteomics. Also new to this edition are discussions of electrosurgical instruments, robotics, imaging modalities, and other emerging technologies influencing the modern practice of surgery. Clinically focused sections in gastrointestinal, vascular, cardiothoracic, transplant, and cancer surgery enable the surgeon to make decisions based upon the most relevant data in modern surgical practice. The text is enhanced by more than 1,000 illustrations and hundreds of the signature evidence-based tables that made the first edition of SURGERY an instant classic.

Twining S Textbook Of Fetal Abnormalities E Book

Author : Anne Marie Coady
ISBN : 9780702054075
Genre : Medical
File Size : 36. 33 MB
Format : PDF, ePub
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Access practical guidance on the radiologic detection, interpretation, and diagnosis of fetal anomalies with Twining’s Textbook of Fetal Abnormalities. With fetal scanning being increasingly done by obstetricians, this updated medical reference book features a brand-new editorial team of radiologist Anne Marie Coady and fetal medicine specialist Sarah Bower; these authorities, together with contributions from many other experts, provide practical, step-by-step guidance on everything from detection and interpretation to successful management approaches. Twining’s Textbook of Fetal Abnormalities is a resource you'll turn to time and again! Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Quickly access specific information with a user-friendly format. Deliver a rapid, reliable diagnosis thanks to a strong focus on image interpretation, as well as the correlation of radiographic features with pathologic findings wherever possible. Clearly visualize a full range of conditions with help from more than 700 images. Stay abreast of the latest developments in detecting fetal abnormalities with 4 brand-new chapters: Fetal Growth; Haematological Disorders; Fetal Pathology; and Fetal Tumours. Access increased coverage of fetal growth, first trimester anomalies, DDX, and clinical management. Understand the major advances in today's hottest imaging technologies, including 3-D Ultrasound, Fetal MRI, and Colour Doppler. Effectively interpret the images you encounter with highly organized coordination between figures, tables, and imaging specimens.

Inflammatory Bowel Disease

Author : Stephan R. Targan
ISBN : 9781444359114
Genre : Medical
File Size : 61. 14 MB
Format : PDF
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This is the state-of–the-art book on inflammatory bowel disease you have been waiting for Written and edited by international experts in gastroenterology this up-to-date volume provides a complete review of the basic science behind inflammatory bowel disease (IBD), as well as evidence-based clinical guidance on diagnosis, treatment and long-term management of IBD. In 50 chapters the authors cover the latest and most promising treatment modalities and the science behind them. There are chapters which cover the advances in the medical and surgical treatment of conditions such as Crohn's disease and ulcerative colitis, as well as chapters focusing on nutrition, imaging and complementary medicine. This is an invaluable information resource for all those in the medical team treating patients with IBD. Whether you are a gastroenterologist, gastrointestinal surgeon or GI nurse specialist this book deserves a place in your library.

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