modeling the psychopathological dimensions of schizophrenia from molecules to behavior handbook of behavioral neuroscience

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Modeling The Psychopathological Dimensions Of Schizophrenia

Author : Mikhail Pletnikov
ISBN : 9780128011843
Genre : Medical
File Size : 21. 3 MB
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Modeling the Psychopathological Dimensions of Schizophrenia: From Molecules to Behavior is the first book to offer a comprehensive review of the new theoretical, clinical, and basic research framework that considers psychotic illness as a group of dimensional representations of psychopathology rather than as traditional distinct categorical diagnoses. Psychotic illness, typified by schizophrenia, is a devastating condition increasingly recognized as a disorder of abnormal brain development and dysconnectivity. Its complex etiology involves both genetic and environmental factors, as well as the interplay among them. This book describes the current understanding of the clinical and pathological features of schizophrenia, with a particular focus on the evolving conceptualization of schizophrenia and related diagnostic categories of psychotic illness as combinations of dimensional abnormalities. It provides an overview of modern strategies for generating cellular and whole animal models of schizophrenia as well as detailed reviews of the specific experimental preparations and paradigms aimed at molecular, developmental, and brain-network mechanisms that are the underlying aspects of abnormal behavior and various aspects of schizophrenia. This groundbreaking book is an authoritative overview of the translational impact of emerging clinical insights on basic research approaches in schizophrenia that will advance the reader’s understanding of the five major dimensions of psychopathology in schizophrenia and related psychoses and resolve the genetic and neurobiological underpinnings of these dimensions. Includes reviews of animal models that capture the most recent insights into the etiology and pathogenetic mechanisms of schizophrenia, with an emphasis on the translational potential of these models Contains a series of reviews of recently available cellular models for analysis of signaling pathways and gene expression, which complement behavioral neuroscience research in schizophrenia Edited and authored by leading researchers in the field of schizophrenia and related psychoses

Handbook Of Psychopathy Second Edition

Author : Christopher J. Patrick
ISBN : 9781462541232
Genre : Medical
File Size : 33. 90 MB
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Widely considered the go-to reference--and now extensively revised with over 65% new material--this authoritative handbook surveys the landscape of current knowledge on psychopathy and addresses essential clinical and applied topics. Leading researchers explore major theoretical models; symptomatology and diagnostic subtypes; assessment methods; developmental pathways; and causal influences, from genes and neurobiology to environmental factors. The volume examines manifestations of psychopathy in specific populations as well as connections to antisocial behavior and recidivism. It presents contemporary perspectives on prevention and treatment and discusses special considerations in clinical and forensic practice. New to This Edition *Extensively revised with more than a decade's theoretical, empirical, and clinical advances. *Many new authors and topics. *Expanded coverage of phenotypic facets, with chapters on behavioral disinhibition, callous–unemotional traits, and boldness. *Chapters on DSM-5, clinical interviewing, cognitive and emotional processing, and serial murder. *Significantly updated coverage of etiology, assessment methods, neuroimaging research, and adult and juvenile treatment approaches.

The Neuropsychopathology Of Schizophrenia

Author : Ming Li
ISBN : 9783319305967
Genre : Psychology
File Size : 60. 59 MB
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One of the first major theoretical reviews of schizophrenia since the publication of the 5th edition of the APA’s Diagnostic and Statistical Manual, the DSM-5, this volume is a landmark in the history of schizophrenia research. It assembles recent groundbreaking developments in research on schizophrenia and reaffirms its central place in the mental health research agenda. Significantly, this volume reflects the paradigmatic shift in schizophrenia research applied in parallel to new approaches in psychiatric diagnosis. New models and findings from across disciplines in recent years reflect a new and greater understanding of the workings of the brain, which, in turn, helps develop our knowledge of the neuro and psychological processes in schizophrenia. Consequently, this volume illustrates a historical convergence of psychology, psychopathology and the neurosciences in schizophrenia. World-renowned leaders of the schizophrenia research community in fields such as neuroscience, p sychiatry, neuropsychology, and clinical psychology offer clear suggestions for further advances in psychological and medical interventions, assessment, prevention strategies, and research. And in keeping with other titles in the Nebraska Symposium on Motivation series, these papers are noteworthy for their depth of detail, scientific rigor, and clinical relevance. Included among the topics: Cognitive organization as a dimension of individual differences and psychopathology. Neurodevelopmental genomic strategies in the study of the psychosis spectrum. Multimodal brain and behavior indices of psychosis risk. The NIMH Research Domain Criteria Project: new approaches to classifying psychotic spectrum disorders. The Neuropsychopathology of Schizophrenia is one of the most forward-thinking and engaging treatments of the field in recent years, and is an i ndispensable text for all researchers, academics, and clinicians who treat or study mental illness, especially psychiatrists, psychologists, mental health practitioners, and neuroscientists specializing in schizophrenia.

Developmental Psychopathology Developmental Neuroscience

Author : Donald J. Cohen
ISBN : 9780470048191
Genre : Psychology
File Size : 55. 33 MB
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This volume applies multiple levels of analysis to neurobiological developmental organization, and functioning in normality and psychopathology. It also covers topics central to a developmental perspective on neuroscience.

Handbook Of Schizophrenia Spectrum Disorders Volume I

Author : Michael S Ritsner
ISBN : 9400708378
Genre : Medical
File Size : 38. 58 MB
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A few disorders have some of the same symptoms as schizophrenia including schizoaffective disorders, schizophreniform disorder, schizotypal and schizoid personality disorders, delusional disorder, and autism (schizophrenia spectrum disorders). Since the 2000 there has been significant progress in our understanding of the early presentations, assessment, suspected neuropathology, and treatment of these disorders. Recent technological breakthroughs in basic sciences hold promise for advancing our understanding of the pathophysiology of schizophrenia spectrum disorders. This collective monograph reviewers recent researches regarding the origins, onset, course, and outcome of schizophrenia spectrum disorders. In particular, this book will be illustrate new developments in terms of conceptual models, and research methodology, genetics and genomics, brain imaging and neurochemical studies, neurophysiology and information processing in schizophrenia spectrum disorders patients. Also will be highlighted new developments in our understanding of the childhood psychosis, prodromal and first-episode states, in treatment and rehabilitation. Thus, the purpose of this book is to provide up-to-date overview of the rapid advances made in the clinical and basic science studies supporting our understanding of the relationship between cerebral processes and clinical, cognitive and other presentations of the schizophrenia spectrum disorders. In addition, this book aims to monitor important research developments, which may be relevant to treatment, and rehabilitation of patients.

Comprehensive Handbook Of Psychopathology

Author : Patricia B. Sutker
ISBN : 0306441691
Genre : Mental illness
File Size : 73. 64 MB
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The third edition of Comprehensive Handbook of Psychopathology provides in-depth coverage of theoretical, research, and clinical positions in psychopathology. Extensively revised and updated, this new edition Outlines a highly improved classification scheme based on the DSM IV; Includes two new chapters on schizophrenia that reflect renewed interest in this topic; Puts new emphasis on cultural and developmental issues; Contains increased coverage of the overlap of medicine and abnormal behavior.?/LIST?? Furnishing both empirical and research data useful to graduate students and practicing clinicians in the mental health profession, particularly clinical psychology, psychiatry, psychiatric nursing, and social work, this handbook is an ideal reference source.

Cumulated Index Medicus

Author :
ISBN : COLUMBIA:HR01642871
Genre : Medicine
File Size : 75. 94 MB
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Dimensional Models Of Personality Disorders

Author : Thomas A. Widiger
ISBN : 1585626732
Genre : Medical
File Size : 57. 24 MB
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DSM-IV and ICD-10 both diagnose personality disorders categorically, yet studies indicate that many patients meet criteria for an excessive number of diagnoses, raising the question of whether personality disorders are discrete conditions or rather distinctions along dimensions of general personality functioning. This collection of papers renews long-standing proposals for a dimensional model of personality disorder, describing alternative models, addressing questions about their clinical application and utility, and suggesting that future research seek to integrate such models within a common hierarchical structure. With contributions by preeminent researchers in the field, Dimensional Models of Personality Disorders is drawn from a conference series convened by APA, WHO, and NIH in order to plan for the fifth edition of the DSM. The Nomenclature Work Group concluded that consideration should be given to basing part or all of DSM-V on dimensions rather than categories, and recommended that a dimensional model for personality disorders should serve as a basis for exploring dimensional approaches in other areas. Accordingly, the volume opens with a presentation of 18 proposals for dimensional models and proceeds with provocative contributions on a number of related issues ranging from hard science to clinical practice. Among the topics addressed are Behavioral and molecular genetic research supporting an etiologically informed dimensional classification of personality disorders The as-yet tenuous associations between dimensional trait measures of personality as contained in the models of Cloninger, Depue, and Siever-Davis, and specific neurobiological measures, as examined in neurotransmitter research Potential links between childhood and adolescent temperament and personality dimensions and adult personality psychopathology Studies examining the covariation of personality dimensions across cultures The continuity of Axis I and Axis II disorders and a proposed hierarchical structure of mental disorders that integrates the psychopathology of Axis I disorders with specific personality traits The dual challenges of coverage and cutoffs that must be addressed if dimensional models are to be considered viable alternatives to the existing categorical diagnostic system Although the editors acknowledge that concerns are certain to be raised regarding conversion to a dimensional classification -- such as the disruption to clinical practice by a radical shift in diagnosing personality disorder -- these papers make a strong case for opening the field to alternative ways of enhancing clinical utility and improving the validity of basic classification concepts. Together, they offer stimulating insight into how we approach personality disorders, with the hope of encouraging a new model of diagnosis for DSM-V.

Handbook Of Personology And Psychopathology

Author : Stephen Strack
ISBN : UOM:39015059149313
Genre : Psychology
File Size : 47. 79 MB
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Personology is the study of human character in all of its complexities, covering the range of normal and pathological individuals, from evolutionary development, classification, diagnosis and measurement, to intervention at the individual, family, and societal levels. This volume, sure to become a classic in the field, provides a state-of-the-art overview of the field of personology, including personality theory, taxonomy, and assessment; diagnosis and treatment of personality disorders; and the interface between normal and abnormal personlity. The breadth and depth of this monumental work and the caliber of its contributors is unsurpassed. * Many of the leading clinicians and researchers in psychology are contributors including Otto Kernberg, John Livesley, Robert Bornstein, Jeffrey Magnavita, Drew Westen, Irving Weiner, and Lorna Benjamin * Represents the culmination of a professional career and a capstone to our publishing program in the area of personality and psychopathology

Human Territoriality

Author : Torsten Malmberg
ISBN : UOM:39015008228960
Genre : Social Science
File Size : 21. 47 MB
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