practical statistics for medical research

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Practical Statistics For Medical Research

Author : Douglas G. Altman
ISBN : 0412276305
Genre : Mathematics
File Size : 21. 30 MB
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Most medical researchers, whether clinical or non-clinical, receive some background in statistics as undergraduates. However, it is most often brief, a long time ago, and largely forgotten by the time it is needed. Furthermore, many introductory texts fall short of adequately explaining the underlying concepts of statistics, and often are divorced from the reality of conducting and assessing medical research. Practical Statistics for Medical Research is a problem-based text for medical researchers, medical students, and others in the medical arena who need to use statistics but have no specialized mathematics background. The author draws on twenty years of experience as a consulting medical statistician to provide clear explanations to key statistical concepts, with a firm emphasis on practical aspects of designing and analyzing medical research. The text gives special attention to the presentation and interpretation of results and the many real problems that arise in medical research.

Practical Statistics For Medical Research

Author : D. G. Altman
ISBN : 0412819309
Genre :
File Size : 57. 19 MB
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Practical Statistical Methods

Author : Lakshmi Padgett
ISBN : 9781439812549
Genre : Mathematics
File Size : 27. 9 MB
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Practical Statistical Methods: A SAS Programming Approach presents a broad spectrum of statistical methods useful for researchers without an extensive statistical background. In addition to nonparametric methods, it covers methods for discrete and continuous data. Omitting mathematical details and complicated formulae, the text provides SAS programs to carry out the necessary analyses and draw appropriate inferences for common statistical problems. After introducing fundamental statistical concepts, the author describes methods used for quantitative data and continuous data following normal and nonnormal distributions. She then focuses on regression methodology, highlighting simple linear regression, logistic regression, and the proportional hazards model. The final chapter briefly discusses such miscellaneous topics as propensity scores, misclassification errors, interim analysis, conditional power, bootstrap, and jackknife. With SAS code and output integrated throughout, this book shows how to interpret data using SAS and illustrates the many statistical methods available for tackling problems in a range of fields, including the pharmaceutical industry and the social sciences.

Regression Methods For Medical Research

Author : Bee Choo Tai
ISBN : 9781118721988
Genre : Medical
File Size : 44. 21 MB
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Regression Methods for Medical Research provides medical researchers with the skills they need to critically read and interpret research using more advanced statistical methods. The statistical requirements of interpreting and publishing in medical journals, together with rapid changes in science and technology, increasingly demands an understanding of more complex and sophisticated analytic procedures. The text explains the application of statistical models to a wide variety of practical medical investigative studies and clinical trials. Regression methods are used to appropriately answer the key design questions posed and in so doing take due account of any effects of potentially influencing co-variables. It begins with a revision of basic statistical concepts, followed by a gentle introduction to the principles of statistical modelling. The various methods of modelling are covered in a non-technical manner so that the principles can be more easily applied in everyday practice. A chapter contrasting regression modelling with a regression tree approach is included. The emphasis is on the understanding and the application of concepts and methods. Data drawn from published studies are used to exemplify statistical concepts throughout. Regression Methods for Medical Research is especially designed for clinicians, public health and environmental health professionals, para-medical research professionals, scientists, laboratory-based researchers and students.

Introduction To Statistical Methods For Clinical Trials

Author : Thomas D. Cook
ISBN : 9781420009965
Genre : Mathematics
File Size : 89. 77 MB
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Clinical trials have become essential research tools for evaluating the benefits and risks of new interventions for the treatment and prevention of diseases, from cardiovascular disease to cancer to AIDS. Based on the authors’ collective experiences in this field, Introduction to Statistical Methods for Clinical Trials presents various statistical topics relevant to the design, monitoring, and analysis of a clinical trial. After reviewing the history, ethics, protocol, and regulatory issues of clinical trials, the book provides guidelines for formulating primary and secondary questions and translating clinical questions into statistical ones. It examines designs used in clinical trials, presents methods for determining sample size, and introduces constrained randomization procedures. The authors also discuss how various types of data must be collected to answer key questions in a trial. In addition, they explore common analysis methods, describe statistical methods that determine what an emerging trend represents, and present issues that arise in the analysis of data. The book concludes with suggestions for reporting trial results that are consistent with universal guidelines recommended by medical journals. Developed from a course taught at the University of Wisconsin for the past 25 years, this textbook provides a solid understanding of the statistical approaches used in the design, conduct, and analysis of clinical trials.

Practical Data Analysis For Designed Experiments

Author : Brian S. Yandell
ISBN : 0412063417
Genre : Mathematics
File Size : 83. 84 MB
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Placing data in the context of the scientific discovery of knowledge through experimentation, Practical Data Analysis for Designed Experiments examines issues of comparing groups and sorting out factor effects and the consequences of imbalance and nesting, then works through more practical applications of the theory. Written in a modern and accessible manner, this book is a useful blend of theory and methods. Exercises included in the text are based on real experiments and real data.

Research Methods For Clinical Therapists E Book

Author : Carolyn M. Hicks
ISBN : 9780702041884
Genre : Medical
File Size : 33. 48 MB
Format : PDF
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Struggling to do a project or dissertation, evaluate published research or conduct your own research? Help is at hand with this 5th edition of Research Methods for Clinical Therapists, which explains, in a clear and simple manner, how to evaluate existing research and how to conduct your own research. Aimed at undergraduate and postgraduate students, as well as the practising health care professional, the focus of the text is the design and analysis of experimental studies. These are vital to the effectiveness studies that are central to the work of the healthcare professional. Specific examples from different areas of healthcare are used to explain the core research concepts and relate them to clinical situations. Statistical theory and jargon are kept to a minimum. 'Key concept' boxes to explain technical research terms Activities and exercises (with answers provided in an appendix) to reinforce learning Sample critique of a published research article Comprehensive coverage of the key components of a robust research study Explanation of basic mathematical concepts Extended section on calculating sample sizes Guidelines on the preparation of posters Calculation of Inter-rater reliability measures, including Cohen’s Kappa, ICC (interclass correlation) and Bland-Altman graphs of inter-rater agreement Introduction to Receiver Operating Characteristics, for use in screening and diagnostic testing against gold-standards The Thurstone Paired Comparison Technique, valuable in capturing the user voice on a variety of service planning, design and development issues Undertaking Systematic Reviews Relevant further reading for each chapter to support readers in their work.

Paediatric Cardiology

Author : Robert H. Anderson
ISBN : 9780702037351
Genre : Medical
File Size : 78. 69 MB
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As patients live longer and need to be treated over the long term and the management of pediatric cardiology problems and congenital heart disease moves more into the mainstream, turn to Pediatric Cardiology for current clinical guidance. Trust Dr. Robert Anderson, godfather of cardiac morphology, to bring you coverage of potential cardiovascular anomalies, all potential diseases related to anomalies or developmental problems, and methods for management and treatment. New contributors from all over the world-including 70% new to this edition-present the latest challenges in the field and emphasize the adolescent and post-operative outcomes for management. Now, in full color, this leading reference offers you everything you need to treat and manage pediatric heart conditions. A comprehensive and exhaustive reference of fundamental and clinical aspects of heart disease in infancy and childhood. The contributors are well-known experts in the field and the editors are a world class group who have published extensively in the field. Emphasizes the treatment of corrected congenital heart disease for coverage of the clinical management of cardiac problems in the adolescent and young adult. Integrates development in chapters on lesions to make physiology clinically relevant for the specific cardiac lesions. Provides the latest clinical perspectives on neonate cardiac development management issues so you can offer the best long-term care. Presents the contributions of 70% new authors, from all over the world, in a consistent format to make referencing global perspectives quick and easy. Captures the nuances of the anatomical structure of lesions through full-color illustrations depicting morphologic, congenital, and surgically corrected examples for exceptional visual guidance.

Statistical Thinking For Non Statisticians In Drug Regulation

Author : Richard Kay
ISBN : 9781118470947
Genre : Medical
File Size : 44. 3 MB
Format : PDF
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Medical Statistics At A Glance

Author : Aviva Petrie
ISBN : 9781118782446
Genre : Medical
File Size : 59. 99 MB
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Medical Statistics at a Glance is a concise and accessible introduction and revision aid for this complex subject. The self-contained chapters explain the underlying concepts of medical statistics and provide a guide to the most commonly used statistical procedures. This new edition of Medical Statistics at a Glance: Presents key facts accompanied by clear and informative tables and diagrams Focuses on illustrative examples which show statistics in action, with an emphasis on the interpretation of computer data analysis rather than complex hand calculations Includes extensive cross-referencing, a comprehensive glossary of terms and flow-charts to make it easier to choose appropriate tests Now provides the learning objectives for each chapter Includes a new chapter on Developing Prognostic Scores Includes new or expanded material on study management, multi-centre studies, sequential trials, bias and different methods to remove confounding in observational studies, multiple comparisons, ROC curves and checking assumptions in a logistic regression analysis The companion website at www.medstatsaag.com contains supplementary material including an extensive reference list and multiple choice questions (MCQs) with interactive answers for self-assessment. Medical Statistics at a Glance will appeal to all medical students, junior doctors and researchers in biomedical and pharmaceutical disciplines. Reviews of the previous editions "The more familiar I have become with this book, the more I appreciate the clear presentation and unthreatening prose. It is now a valuable companion to my formal statistics course." –International Journal of Epidemiology "I heartily recommend it, especially to first years, but it's equally appropriate for an intercalated BSc or Postgraduate research. If statistics give you headaches - buy it. If statistics are all you think about - buy it." –GKT Gazette "...I unreservedly recommend this book to all medical students, especially those that dislike reading reams of text. This is one book that will not sit on your shelf collecting dust once you have graduated and will also function as a reference book." –4th Year Medical Student, Barts and the London Chronicle, Spring 2003

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