reproductive-toxicology

Download Book Reproductive Toxicology in PDF format. You can Read Online Reproductive Toxicology here in PDF, EPUB, Mobi or Docx formats.

Reproductive Toxicology

Author : Jesús del Mazo
ISBN : 9781489900890
Genre : Medical
File Size : 23. 35 MB
Format : PDF, Docs
Download : 731
Read : 640

Get This Book


Numerous reports demonstrate that the reproductive system could be affected by multiple potential toxicological agents. The volume includes different aspects of the development of new approaches to in vitro testing using sperm cells and systems involved on reproduction in mammals. Comparative analysis of in vivo and in vitro methods has been included to take steps towards the further development of and applications of new systems for germline toxicology.

Reproductive Toxicology

Author : Mervyn Richardson
ISBN : CORNELL:31924062873264
Genre : Medical
File Size : 51. 8 MB
Format : PDF, ePub
Download : 781
Read : 357

Get This Book


Reproductive toxicology is a subject of crucial importance to future generations. Toxic exposure of the developing embryo is a well-recognized problem, but it is also necessary to consider the effects of certain chemicals prior to conception, both in humans and in animals. The mechanisms and routes of the biological action need to be established. The book surveys the effects of chemical substances on female and male reproductive systems. Both the legislative and regulatory positions are summarized. Whilst the EC is currently preparing legislation to control exposures to pregnant and nursing mothers, equal attention is required for similar hazards to males. More than 1000 references guide the reader to the current international literature. Physicians, epidemiologists, toxicologists, chemists, and biologists in academia, industry, government and UN agencies will find in this book an invaluable survey of modern thinking on reproductive toxicology

Reproductive Toxicology

Author : Donald R. Mattison
ISBN : UOM:39015004411321
Genre : Reproduction
File Size : 28. 76 MB
Format : PDF, Mobi
Download : 383
Read : 913

Get This Book



Reproductive Toxicology Third Edition

Author : Robert W. Kapp
ISBN : 9781420073447
Genre : Medical
File Size : 33. 82 MB
Format : PDF
Download : 859
Read : 752

Get This Book


Thoroughly examining the popular and expanding field of reproductive toxicology, this newly revised and expanded third edition provides the latest, cutting-edge scientific developments in this constantly evolving discipline. Reproductive Toxicology’s contributors are experienced regulatory agency and Clinical Research Organization representatives who currently utilize the new techniques discussed in the text and continue to revolutionize reproductive toxicology research. This ground-breaking resource includes: New and important critical mechanistic topics such as epigenetics and omics The first significant compilation of epigenetic mechanisms An in-depth analysis of the role of genomics, proteomics, and metabolomicsin human reproduction New guidelines with respect to the latest research applications in the field

Developmental And Reproductive Toxicology

Author : Ronald D. Hood
ISBN : 9781420040548
Genre : Medical
File Size : 69. 44 MB
Format : PDF
Download : 408
Read : 1242

Get This Book


Completely revised and updated, Developmental and Reproductive Toxicology: A Practical Approach, Second Edition draws together valuable information typically scattered throughout the literature, plus some not previously published, into one complete resource. In addition to the traditional aspects of developmental toxicity testing, the book covers evaluating and interpreting data. Originally titled Handbook of Developmental Toxicology, the second edition's new name reflects significant changes in its content and scope. New coverage in the Second Edition: Genomics and proteomics Tests for endocrine disruptors Testing for male and female reproductive toxicity Extensive treatment of the significance, reliability, and interpretation of developmental and reproductive toxicity data Toxicity testing in neonatal and juvenile animals Postnatal developmental milestones FDA perspective on risk assessment Extensive glossaries of developmental defect terminology Previous books on this subject have largely been academically oriented and not intended to guide the practicing developmental or reproductive toxicologist. Useful and informative, this book blends the theoretical foundation with insights gained from hands-on experience. It includes tables of comparative developmental milestones - both pre- and postnatal, glossaries of descriptive terms used in developmental toxicity evaluation, and both US and international regulatory guidelines. Bridging the gap between theory and application, this is a handy single-source of essential information to use in planning, conducting, and interpreting studies.

Male Reproductive Toxicology

Author : Robert E. Chapin
ISBN : 9781483270951
Genre : Medical
File Size : 40. 86 MB
Format : PDF, ePub, Mobi
Download : 999
Read : 856

Get This Book


Methods in Toxicology, Volume 3: Male Reproductive Toxicology, Part A, deals with the male reproductive system and discusses methods that will help identify toxicant-induced changes at all levels in living organisms. It is important to realize that a toxic effect does not occur in a vacuum. All work in toxicology must be predicated on a demonstrated adverse effect in vivo. If good toxicology cannot exist in a vacuum, then there must be a structure. Thus, the book begins by presenting a few models as examples of the ways experiments could be grouped to define the toxicity of a chemical. This is followed by separate chapters on methods such as male mouse sexual behavior test; in vitro techniques for assessing pituitary secretory function; histological methods for preservation of the rat testis; procedures for assessing testicular sperm head counts in mice, rats, and dogs; and guidelines for conducting rodent dominant lethal tests. Subsequent chapters cover topics such as methods for the isolation and purification of Leydig cells from rat and mouse testes, and techniques used in semen analysis and fertility assessment in the rabbit.

Multigenerational Reproductive Toxicology Study Of Ethinyl Estradiol Cas No 57636 In Spraguedawley Rats Feed Studies

Author :
ISBN : 9781437942316
Genre :
File Size : 74. 79 MB
Format : PDF, Kindle
Download : 489
Read : 985

Get This Book



Reproductive Toxicology Second Edition

Author : J Witorsch Raphael
ISBN : 0781702259
Genre : Medical
File Size : 80. 19 MB
Format : PDF, Mobi
Download : 833
Read : 833

Get This Book


Presents not only the major principles and current issues in the field but also provides a physiologic basis for the actions and reactions to reproductive toxic agents. The volume is divided into three sections. The first focuses on the current concepts of normal mammalian reproductive function from the systems to subcellular level. The second explains how toxic substances disrupt the normal functioning of elements of the mammalian reproductive system. The third section discusses other issues of long-standing or recent interest to the field, such as clinical aspects, epidemiology, and the toxic effects of low-energy electromagnetic fields and tobacco, alcohol, and other substances of abuse. Annotation copyright by Book News, Inc., Portland, OR

Biologic Markers In Reproductive Toxicology

Author : National Research Council
ISBN : 0309039797
Genre : Social Science
File Size : 65. 82 MB
Format : PDF
Download : 568
Read : 749

Get This Book


Does exposure to environmental toxicants inhibit our ability to have healthy children who develop normally? Biologic markersâ€"indicators that can tell us when environmental factors have caused a change at the cellular or biochemical level that might affect reproductive abilityâ€"are a promising tool for research aimed at answering that important question. Biologic Markers in Reproductive Toxicology examines the potential of these markers in environmental health studies; clarifies definitions, underlying concepts, and possible applications; and shows the benefits to be gained from their use in reproductive and neurodevelopmental research.

Reproductive And Developmental Toxicology

Author : Kenneth S . Korach
ISBN : 1420002899
Genre : Medical
File Size : 21. 88 MB
Format : PDF
Download : 179
Read : 432

Get This Book


This timely resource offers extensive discussions on the pharmacological, environmental,endocrinological, and natural factors that alter reproductive or developmental processes-elucidating the effects of toxicants on mechanisms of reproduction. Describing biological actions common to both genders as well as gender-specific processes, Reproducti

Developmental Toxicology

Author : CaroleAKimmel
ISBN : 0781701376
Genre : Medical
File Size : 83. 20 MB
Format : PDF, Mobi
Download : 553
Read : 729

Get This Book


The Second Edition of this highly regarded work provides a state-of-the-art review of developmental toxicology from basic science, clinical, epidemiological, and regulatory perspectives. This new edition highlights the latest approaches to understanding the mechanisms of developmental toxicity, testing pharmaceutical and environmental agents, and interpreting developmental toxicity data.; The contributors demonstrate how new information on molecular embryology and cell biology is being applied to problems in developmental toxicology. Chapters describe the effects of toxic exposure on the functional development of various organs, examine the relationship between maternal and developmental toxicity, and discuss current techniques for studying chemical disposition, metabolism, and placental transfer. Close attention is given to the use of mathematical and statistical techniques in data interpretation, as well as to the regulatory aspects of testing and risk assessment. Other chapters focus on pre- and post conceptional clinical care and on genetic factors in clinical developmental toxicology.

Reproductive And Developmental Toxicology

Author : Ramesh C. Gupta
ISBN : 9780128042403
Genre : Medical
File Size : 21. 20 MB
Format : PDF, ePub
Download : 594
Read : 391

Get This Book


Reproductive and Developmental Toxicology, Second Edition, is a comprehensive and authoritative resource that provides the latest literature on this complex subject with a primary focus on three core components—parent, placenta, and fetus—and the continuous changes that occur in each. Enriched with relevant references describing every aspect of reproductive toxicology, this revised and updated resource addresses the totality of the subject, discussing a broad range of topics, including nanoparticles and radiation, gases and solvents, smoking, alcohol and drug abuse, and metals, amongst others. With a special focus on placental toxicity, this book is the only available reference to connect the three key risk stages, also including discussions on reproductive and developmental toxicity in domestic animals, fish, and wildlife. Completely revised and updated to include the most recent developments in the field, the book is an essential resource for advanced students and researchers in toxicology, as well as biologists, pharmacologists, and teratologists from academia, industry, and regulatory agencies. Provides a complete, up-to-date, integrated source of information on the key risk stages during reproduction and development Includes new chapters covering significant developments, such as dose-response assessment for developmental toxicity, juvenile toxicity, and neural tube defects, as well as emerging science, such as stem cell application, toxicoproteomics, metabolomics, endocrine disruption, surveillance and regulatory considerations, and risk assessment Offers diverse and unique in vitro and in vivo toxicity models for reproductive and developmental toxicity testing in a user-friendly format that assists in comparative analysis

Male Reproductive Toxicology

Author : Philip Wexler
ISBN : MINN:31951002877301M
Genre : Generative organs, Male
File Size : 81. 46 MB
Format : PDF
Download : 556
Read : 407

Get This Book



Reviews In Environmental Health 1997

Author :
ISBN : OCLC:36762750
Genre : Chemical senses
File Size : 87. 67 MB
Format : PDF, Mobi
Download : 302
Read : 829

Get This Book



Physiology And Toxicology Of Male Reproduction

Author : James C. Lamb
ISBN : 9781483272078
Genre : Health & Fitness
File Size : 60. 53 MB
Format : PDF, Docs
Download : 426
Read : 368

Get This Book


Physiology and Toxicology of Male Reproduction is a collection of papers that deals with general reproductive biology and specific aspects of reproductive toxicology, pertaining to the male sex. Some papers discuss testicular organization, reproductive toxicity testing systems, and germ-cell genetic toxicology. The use of in vitro systems by investigators to dissect the male reproductive toxicants can lead to a more scientific approach toward hazard assessment and the development of safer drugs and chemicals. Other papers explain the fundamental reproductive biology of the testis, the neuroendocrine system, the epididymis and accessory sex organs, and spermatozoal evaluation. Toxicological aspects cover the toxicological evaluation of the complete reproductive system, testicular morphology, sperm assessment, and germ-cell mutagenesis. One paper describes alternative methods in toxicology—by using new in vitro systems that should reduce or eliminate the need for tests conducted on animals. In vitro methodology embraces other systems such as from subcellular fractions to isolated intact organs. In relation to target-organ toxicity, the researcher can focus using primary cell cultures. This collection will prove helpful to toxicologists, graduate students and researchers in biology, particularly in male reproductive toxicology and fertility testing.

Principles And Methods Of Toxicology Fifth Edition

Author : A. Wallace Hayes
ISBN : 084933778X
Genre : Medical
File Size : 48. 60 MB
Format : PDF, ePub
Download : 269
Read : 257

Get This Book


Founded on the paradox that all things are poisons and the difference between poison and remedy is quantity, the determination of safe dosage forms the base and focus of modern toxicology. In order to make a sound determination there must be a working knowledge of the biologic mechanisms involved and of the methods employed to define these mechanisms. While the vastness of the field and the rapid accumulation of data may preclude the possibility of absorbing and retaining more than a fraction of the available information, a solid understanding of the underlying principles is essential. Extensively revised and updated with four new chapters and an expanded glossary, this fifth edition of the classic text, Principles and Methods of Toxicology provides comprehensive coverage in a manageable and accessible format. New topics include 'toxicopanomics', plant and animal poisons, information resources, and non-animal testing alternatives. Emphasizing the cornerstones of toxicology-people differ, dose matters, and things change, the book begins with a review of the history of toxicology and followed by an explanation of basic toxicological principles, agents that cause toxicity, target organ toxicity, and toxicological testing methods including many of the test protocols required to meet regulatory needs worldwide. The book examines each method or procedure from the standpoint of technique and interpretation of data and discusses problems and pitfalls that may be associated with each. The addition of several new authors allow for a broader and more diverse treatment of the ever-changing and expanding field of toxicology. Maintaining the high-quality information and organizational framework that made the previous editions so successful, Principles and Methods of Toxicology, Fifth Edition continues to be a valuable resource for the advanced practitioner as well as the new disciple of toxicology.

Cumulated Index Medicus

Author :
ISBN : UIUC:30112001088373
Genre : Medicine
File Size : 26. 24 MB
Format : PDF
Download : 257
Read : 1004

Get This Book



Handbook Of Developmental Toxicology

Author : Ronald D. Hood
ISBN : 0849301351
Genre : Medical
File Size : 47. 63 MB
Format : PDF, Docs
Download : 268
Read : 1246

Get This Book


Developmental toxicology, an increasingly important area, encompasses the study of toxicant effects on development, from conception through puberty. The Handbook of Developmental Toxicology provides useful insights gained from hands-on experience, as well as a theoretical foundation. In this convenient reference you will find information not previously gathered in one source-including comparative developmental milestones, historical data, and a glossary of terms used in developmental toxicity evaluation. This handbook is a practical guide for individuals who are responsible for testing chemical agents and for regulatory scientists who must evaluate studies, interpret data, and perform risk assessments. Packed with features, the Handbook of Developmental Toxicology is ideal for training students and technicians in developmental toxicology.

Reproductive Toxicology

Author : Robert Louis Dixon
ISBN : UCSC:32106006936709
Genre : Medical
File Size : 59. 84 MB
Format : PDF, Docs
Download : 492
Read : 882

Get This Book



Handbook Of Toxicology

Author : Michael J. Derelanko
ISBN : 9781439890141
Genre : Law
File Size : 75. 80 MB
Format : PDF, ePub
Download : 332
Read : 1191

Get This Book


The Handbook of Toxicology, Third Edition provides an updated practical reference source for practicing toxicologists in the pharmaceutical and chemical industries, contract laboratories, regulatory agencies, and academia. Written by experts in their specific toxicology fields, the chapters provide both fundamental and applied information. Topics r

Top Download:

Best Books