the biology of tumors

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The Biology Of Cancer

Author : Weinberg, Robert A.
ISBN : 9780815345282
Genre : Science
File Size : 79. 44 MB
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Incorporating the most important advances in the fast-growing field of cancer biology, the text maintains all of its hallmark features. It is admired by students, instructors, researchers, and clinicians around the world for its clear writing, extensive full-color art program, and numerous pedagogical features.

Molecular Biology Of Cancer

Author : Fiona Macdonald
ISBN : 9780203503447
Genre : Science
File Size : 44. 67 MB
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Molecular Biology of Cancer has been extensively revised and covers heredity cancer, microarray technology and increased study of childhood cancers. It continues to provide a detailed overview of the process which lead to the development and proliferation of cancer cells, including the techniques available for their study. It also describes the means by which tumor suppressor genes and oncogenes may be used in the diagnosis and in determining the prognosis of a wide variety of cancers, including breast, genitourinary, lung and gastrointestinal cancer.

The Biology Of Cancer

Author : Robert Allan Weinberg
ISBN : 0815340788
Genre : Science
File Size : 40. 98 MB
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Accompanying CD-ROM contains ... "figures from text--in PowerPoint and JPEG formats; supplementary sidebars; mini-lectures; movies."--CD-ROM label.

The Molecular Biology Of Cancer

Author : Stella Pelengaris
ISBN : 9781118430859
Genre : Science
File Size : 72. 78 MB
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The Molecular Biology of Cancer, Stella Pelengaris& Michael Khan This capturing, comprehensive text, extensively revisedand updated for its second edition, provides a detailed overview ofthe molecular mechanisms underpinning the development of cancer andits treatment. “Bench to Bedside”: A key strength of thisbook that sets it apart from general cancer biology references isthe interweaving of all aspects of cancer biology from the causes,development and diagnosis through to the treatment and care ofcancer patients – essential for providing a broader view ofcancer and its impact. The highly readable presentation of a complex field,written by an international panel of researchers, specialists andpractitioners, would provide an excellent text for graduate andundergraduate courses in the biology of cancer, medical studentsand qualified practitioners in the field preparing for higherexams, and for researchers and teachers in the field. For the teaching of cancer biology, special features havebeen included to facilitate this use: bullet points at thebeginning of each chapter explaining key concepts and controversialareas; each chapter builds on concepts learned in previouschapters, with a list of key outstanding questions remaining in thefield, suggestions for further reading, and questions for studentreview. All chapters contain text boxes that provide additional andrelevant information. Key highlights are listed below: An overview of the cancer cell and important newconcepts. Selected human cancers: lung, breast, colorectal, prostate,renal, skin, cervix, and hematological malignancies. Key cellular processes in cancer biology including (a)traditionally important areas such as cell cycle control, growthregulation, oncogenes and tumour suppressors apoptosis, as well as(b) more highly topical areas of apoptosis, telomeres, DNA damageand repair, cell adhesion, angiogenesis, immunity, epigenetics, andthe proteasome. Clinical oncology: In-depth coverage of important concepts suchas screening, risk of cancer and prevention, diagnoses, managingcancer patients from start to palliative care and end-of-lifepathways. Chapters highlighting the direct links between cancer researchand clinical applications. New coverage on how cancer drugs are actually used inspecific cancer patients, and how therapies are developed andtested. Systems Biology and cutting edge research areas covered such asRNA interference (RNAi). Each chapter includes key points, chapter summaries, textboxes, and topical references for added comprehension andreview. Quotations have been used in each chapter to introduce basicconcepts in an entertaining way. Supported by a dedicated website at ahref="http://www.blackwellpublishing.com/pelengaris"www.blackwellpublishing.com/pelengaris/a We should list the great reviews we got for first editionwhich are on the back of the 2nd edition: “A capturing, comprehensive, clearly written andabsolutely accurate introduction into cancer biology…..Thisbook deserves great praise for the readable presentation of thiscomplex field….the true synthesis of bench and bedsideapproaches is marvelously achieved.” Christian Schmidt,Molecular Cell “Chapters address the issues of cancer diagnosis,treatment, and patient care and set the book apart from generalmolecular biology references….This book is applicable to bothgraduate and undergraduate students, and in the context of aresearch laboratory, this book would be an excellent resource as areference guide for scientists at all levels.” V.Emuss,Institute of Cancer Research, London. Also, from the first edition: “Pelengaris, Khan, and the contributing authors are to beapplauded. The Molecular Biology of Cancer is acomprehensive and readable presentation of the many faces of cancerfrom molecular mechanisms to clinical therapies and diagnostics.This book will be welcomed by neophyte students, establishedscientists in other fields, and curious physicians.” -DeanFelsher, Stanford University

The Biology Of Tumors

Author : Enrico Mihich
ISBN : 9781489913524
Genre : Medical
File Size : 62. 61 MB
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The Ninth Annual Pezcoller Symposium entitled "The Biology of Tumors" was held in Rovereto, Italy, June 4-7, 1997. It focused on the genetic mechanisms underlying het erogeneity of tumor cell populations and tumor cell differentiation, on interactions be tween tumor cells and cells of host defenses, and the mechanisms of angiogenesis. With presentations at the cutting edge of progress and stimulating discussions, this symposium addressed issues related to phenomena concerned with cell regulation and cell interactions as determined by activated genes through the appropriate and timely media tion of gene products. Important methodologies that would allow scientists to measure dif ferentially genes and gene products and thus validate many of the mechanisms of control currently proposed were considered, as were the molecular basis of tumor recognition by the immune system, interactions between cells and molecular mechanisms of cell regula tion as they are affected by or implemented through these interactions. The molecular and cellular mechanisms of tumor vascularization were also discussed. It was recognized that angiogenesis provides a potential site of therapeutic intervention and this makes it even more important to understand the mechanisms underlying it. We wish to thank the participants in the symposium for their substantial contribu tions and their participation in the spirited discussions that followed. We would also like to thank Drs.

Biology Of Tumors Cellular Biology And Growth

Author : Frederick Becker
ISBN : 146849953X
Genre : Medical
File Size : 52. 35 MB
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As was shown in the first two volumes of this series, great strides have been made in identifying many of the agents or classes of substances responsible for carcinogenesis and in delineating their interactions with the cell. Clearly, the aim of such studies is that, once identified, these agents can be eliminated from the environment. Yet, despite these advances and the elimination of some important carcinogenic agents, one major problem exists. It is a constant monitor of all oncologic study and diminishes the importance of every experiment and of every clinical observation. As we noted earlier, that problem is our inability to define the malignant cell. It is through studies of the fundamental biology of tumors that we seek this definition. A vast amount of information has been gathered which describes what this cell does and-to a lesser extent-how it does it. But the why evades us. We have been unable to define the malignant cell, save in broad terms by comparing it to its normal counterpart. The major problem appears to be that the malignant cell does so much. It is a chimera, mystifyingly composed of normal activities and structures, of phenotypic schizophrenia with embryonic, fetal, and adult charac teristics and, occasionally, a hint of an unclassifiable capacity unique to malignant cells.

Molecular Biology Of Cancer

Author : Lauren Pecorino
ISBN : 9780199577170
Genre : Medical
File Size : 63. 87 MB
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The third edition of The Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics offers a fresh approach to the study of the molecular basis of cancer, by showing how our understanding of the defective mechanisms which drive cancer is leading to the development of new targeted therapeutic agents.

Molecular And Cell Biology Of Cancer

Author : Rita Fior
ISBN : 9783030118129
Genre :
File Size : 63. 84 MB
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This textbook takes you on a journey to the basic concepts of cancer biology. It combines developmental, evolutionary and cell biology perspectives, to then wrap-up with an integrated clinical approach. The book starts with an introductory chapter, looking at cancer in a nut shell. The subsequent chapters are detailed and the idea of cancer as a mass of somatic cells undergoing a micro-evolutionary Darwinian process is explored. Further, the main Hanahan and Weinberg "Hallmarks of Cancer" are revisited. In most chapters, the fundamental experiments that led to key concepts, connecting basic biology and biomedicine are highlighted. In the books closing section all of these concepts are integrated in clinical studies, where molecular diagnosis as well as the various classical and modern therapeutic strategies are addressed. The book is written in an easy-to-read language, like a one-on-one conversation between the writer and the reader, without compromising the scientific accuracy. Therefore, this book is suited not only for advanced undergraduates and master students but also for patients or curious lay people looking for a further understanding of this shattering disease.

Studies In The Biology Of Tumor Cells

Author : Howard William Travis
ISBN : 9781172257799
Genre : History
File Size : 78. 88 MB
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Cancer

Author : Vincent T. DeVita
ISBN : 9781451118971
Genre : Medical
File Size : 53. 29 MB
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Drawn from the content of the new Ninth Edition of Cancer: Principles and Practice of Oncology, this unique publication brings together the basic scientific information on the molecular biology of cancer. The format is designed to be useful both to research scientists interested in the study of cancer and to oncologists who need to understand these new developments that are having a profound impact on the care of patients with cancer. Leading scientists and clinicians in the field of molecular biology and clinical oncology have lent their expertise to this project. The text has been divided into two parts. Part I includes thirteen chapters that deal with the general principles of the molecular biology of cancer that provide the basic framework for an understanding of the behavior of cancer cells. Part II includes an up-to-date description of how this new information has affected the understanding of the biology of 19 of the most common cancers, with an emphasis on how these new findings have been translated to impact the management of cancer patients. This distinctive text provides a single concise source of information for scientists and clinicians in this rapidly developing field.

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