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The Genetics Of Male Infertility

Author : Douglas T. Carrell
ISBN : 9781597451765
Genre : Medical
File Size : 31. 22 MB
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In this book, twenty-one researchers and clinicians review the study of the genetics of male infertility, the tools available in the laboratory and clinic, the current state of knowledge, and the future of research and translation into clinical diagnostics and treatments. New tools discussed are discussed. This book therefore serves as a guide to evidence-based clinical applications, and a preview of future possibilities.

The Genetic Basis Of Male Infertility

Author : Ken McElreavey
ISBN : 3540662642
Genre : Medical
File Size : 72. 19 MB
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Every year there are new and exciting developments in assisted human reproduction, but how much do we really know about the underlying causes of infertility? This volume explores recent progress in the understanding of the genetics of spermatogenesis and male infertility. Topics include fundamental advances and current problems in the development and function of the testis, an outline of clinical findings in male infertility and an overview of the role of the Y chromosome in male fertility. Comprehensive critiques of posttranscriptional control during spermatogenesis, mammalian meiotic sterility, and comparative genetics of human spermatogenesis from the perspective of yeast, Drosophila and mice provide a global overview of the field.

Genetics Of Male Infertility

Author : Mohamed Arafa
ISBN : 9783030379728
Genre : Health & Fitness
File Size : 36. 38 MB
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This unique, case-based guide provides a thoughtful and comprehensive overview of the genetic basis of male infertility for the practicing clinician. In addition to discussing the molecular foundations of sperm production and the consequences of genetic abnormalities on various stages of sperm development, it examines the clinical aspects of acknowledged genetic disorders and their implications on male fertility. In so doing, it offers the necessary tools required by the clinician for the diagnosis and treatment of infertile men with genetic abnormalities. Moreover, it provides essential algorithms that may aid in counseling patients in the clinic. The text is arranged in four thematic sections for easy reference. The genetic foundation of male reproduction is presented in part 1, including regulation of sperm production, the structure of sperm chromatin, and spermatogenesis. The impact of genetic abnormalities on male infertility is the subject of part 2, covering sperm defects, mitochondrial function and DNA fragmentation. The clinical case material in part 3 illustrates real-world examples of genetic etiologies and the current diagnostic and therapeutic strategies for conditions such as vas asplasia, cryptorchidism, immotile cilia syndrome, sperm aneuploidy and other challenging scenarios. Casting forward, the fourth and final section presents an overview of future possibilities for management of genetic causes of male infertility, including gene editing. Fully exploring the clinical context of these genetic conditions in a practical manner that appeals to the practicing clinician, Genetics of Male Infertility is an exciting and essential text for reproductive medicine specialists, andrologists, urologists, researchers and all other clinicians treating infertile patients.

Genetics Of Human Infertility

Author : P.H. Vogt
ISBN : 9783318060980
Genre : Medical
File Size : 49. 48 MB
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Infertility affects more than one in ten couples worldwide and is related to highly heterogeneous pathologies sometimes only discernible in the germ line. Its complex etiology often, but not always, includes genetic factors besides anatomical defects, immunological interference, and environmental aspects. Nearly 30% of infertility cases are probably caused only by genetic defects. Thereby experimental animal knockout models convincingly show that infertility can be caused by single or multiple gene defects. Translating those basic research findings into clinical studies is challenging, leaving genetic causes for the vast majority of infertility patients unexplained. Nevertheless, a large number of candidate genes have been revealed by sophisticated molecular methods. This book provides a comprehensive overview on the subject of infertility written by the leading authorities in this field. It covers topics including basic biological, cytological, and molecular studies, as well as common and uncommon syndromes. It is a must-read for human geneticists, endocrinologists, epidemiologists, zoologists, and counsellors in human genetics, infertility, and assisted reproduction.

The Male Gamete

Author : Claude Gagnon
ISBN : CORNELL:31924087259184
Genre : Science
File Size : 85. 82 MB
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Fertility And Reproductive Medicine

Author : Roger D. Kempers
ISBN : UOM:39015041780670
Genre : Medical
File Size : 78. 99 MB
Format : PDF
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Hardbound. Fertility and Reproductive Medicine is a compilation of approximately 70 state-of-the-art lectures given by international authorities in basic science and clinical investigation in reproductive medicine. The result is anexcellent blending of contemporary, factual information most specifically focused on three categories - Reviews, Practice and Research.Articles from the Review section range from updates on current investigation in polycystic ovarian disease (PCOD), to microlaparoscopy technology for tubal factor infertility, and legal and ethical considerations of assisted reproductive technology. Articles in the Practice section include the latest clinical studies in ovulation induction regimens, the most effective management of the different stages of endometriosis, and the most current recommendations for the management of menopause. Articles in the Research sections report on a wide variety of invest

Male Infertility Understanding Causes And Treatment

Author : RAJENDER SINGH
ISBN : 9789811040177
Genre : Medical
File Size : 70. 81 MB
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This book covers the latest research on male infertility. The topics discussed range from understanding the genetic basis of infertility, to its causes and treatment. Since infertility is also of great interest to the general public, the book also includes a detailed description of what infertility is and how one can understand the different types. Given the complex etiology of infertility, the book includes a number of chapters defining the known and probable causes of male infertility. Providing detailed information suitable for patients and clinicians alike, it also features a separate section on treatment, the ultimate goal.

Folia Biologica

Author :
ISBN : STANFORD:36105121682491
Genre : Biology
File Size : 64. 92 MB
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The Infertility Manual

Author : Kamini A. Rao
ISBN : UOM:39015063088622
Genre : Medical
File Size : 38. 30 MB
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CD-ROM includes video files of material discussed in text.

Mouse Genetics After The Mouse Genome

Author : Silvia Garagna
ISBN : STANFORD:36105114252575
Genre : Medical
File Size : 87. 79 MB
Format : PDF
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The house mouse holds a unique place among model organisms, representing an indispensable tool for many investigators, particularly in biomedical research. Mouse genetics encompasses nearly 100 years of research and culminated in the publication of the mouse genome sequence in 2002, from which the idea for this special issue arose. The issue features 37 peer-reviewed papers providing a wide-ranging overview of all major aspects of mouse genetics, from nuclear transfer and embryonic development to cancer, from reproduction to speciation and functional genomics technologies. Its aim is to present a suitable tool of investigation for the large population of researchers that use the mouse as a model animal. Covering a variety of topics, this publication will be a useful guide for scientists working in the fields of reproduction, development, evolution, cancer, toxicology, and cell biology as well as for beginners entering the world of mouse genetics.

Molecular Signaling In Spermatogenesis And Male Infertility

Author : Rajender Singh
ISBN : 0429244215
Genre : Medical
File Size : 77. 13 MB
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"Spermatogenesis involves the coordination of a number of signaling pathways, which culminate into production of sperm. Its failure results in male factor infertility, which can be due to hormonal, environmental, genetic or other unknown factors. This book inludes chapters on most of the signaling pathways known to contribute to spermatogenesis"--

Surgical And Medical Management Of Male Infertility

Author : Marc Goldstein
ISBN : 9780521881098
Genre : Medical
File Size : 54. 23 MB
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Written by world-renowned experts, this textbook comprehensively covers the evaluation, treatment and prevention of male infertility.

Human Genetics

Author : Ricki Lewis
ISBN : UCSD:31822037483252
Genre : Medical
File Size : 28. 36 MB
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Explains what genes are, how they function, how they interact with the environment, and how our understanding of genetics has changed since completion of the human genome project.

Encyclopedia Of Endocrine Diseases E Im

Author : Luciano Martini
ISBN : 0124755720
Genre : Endocrine glands
File Size : 59. 70 MB
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The Encyclopedia of Endocrine Diseases is an authoritative reference developed by 16 international experts who recruited the world's top scientists for contributions. This stellar reference work focuses on nearly 500 endocrine diseases addressing everything from acromeglay, diabetes, hypertension, osteoporosis, thyroid disease, Von Hippel-Lindau Disease, unexplained weight loss, to androgen related disorders. This encyclopedia is an essential addition to any library collection written to be accessible for both the clinical and non-clinical reader. Associate Editors include: Eli Y. Adashi, John P. Bilezikian, George P. Chrousos, Junichi Fukata, Julianne Imperato-McGinley, Hiroo Imura, Antonio Liuzzi, Frank L. Moore, Daniel Porte, Jens F. Rehfeld, Ellis Samols, Gustav Schonfeld, Pierre C. Sizonenko, Wilmar M. Wiersinga. Also available online via ScienceDirect featuring extensive browsing, searching, and internal cross-referencing between articles in the work, plus dynamic linking to journal articles and abstract databases, making navigation flexible and easy. For more information, pricing options and availability visit www.info.sciencedirect.com. * Includes nearly 500 entries addressing all aspects of endocrine diseases * More than 800 eminent researchers contributed from 25 different countries around the world * More than 900 figures and 450 tables displayed * Comprehensive glossary comprising 1500 definitions * The Editor-in-Chief is former editor of the journal Frontiers in Neuroendocrinology and has contributed to over 40 books in the field of endocrinology.

Fundamentals Of Male Infertility

Author : Sherman Silber
ISBN : 9783319765235
Genre : Health & Fitness
File Size : 20. 32 MB
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This book analyzes the basic science and treatment of male factor infertility with Dr. Silber’s characteristic honesty and clear thinking. It describes finally what works and what doesn’t work. It will inspire everyone in reproductive medicine (Gynecologists, Urologists, Embryologists and Endocrinologists) who wish to better understand male infertility.

Indian Journal Of Physiology And Pharmacology

Author :
ISBN : OSU:32435070116868
Genre : Pharmacology
File Size : 77. 17 MB
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Women S Health

Author :
ISBN : UOM:39015037633537
Genre : Gynecology
File Size : 30. 21 MB
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The Genetics And Biology Of Drosophila

Author : M. Ashburner
ISBN : WISC:89030490700
Genre : Science
File Size : 26. 28 MB
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Male Infertility

Author : Edmund S. Sabanegh, Jr.
ISBN : 1607611937
Genre : Medical
File Size : 55. 93 MB
Format : PDF, Kindle
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Male Infertility: Problems and Solutions provides a summary of state of the art developments in male infertility for both new and experienced practitioners. Written in a clear, concise and readable style, this volume allows the reader to obtain rapid answers to this challenging medical issue. Special emphasis is placed on diagnostic and treatment algorithms. Topics covered include interpretation of semen analysis and advanced testing, endocrine and genetic evaluation, diagnosis of azoospermia as well as an up-to-date interpretation and analysis of the many new therapies available for the treatment of male factor infertility. Male Infertility: Problems and Solutions provides rapid acquisition of pertinent background and development of management plans through the use of concise discussion and treatment algorithms and thus will be of great value to general urologists, gynecologists, primary care providers and allied health providers who manage infertility in both men as well as women.

Proceedings

Author : Indian National Science Academy
ISBN : CHI:66269541
Genre : Biology
File Size : 87. 31 MB
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