the neuroimmunological basis of behavior and mental disorders

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The Neuroimmunological Basis Of Behavior And Mental Disorders

Author : Allan Siegel
ISBN : 9780387848518
Genre : Medical
File Size : 49. 23 MB
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For many years, the immune and central nervous systems were thought to function independently with little or no interaction between the two. This view has und- gone dramatic changes over the past three decades. Indeed, we now know that there exists various feedback loops between the brain and immune systems that impact signi cantly upon different behavioral processes, including normal behavior and mental disorders. Pioneering efforts in generating this change were initiated by a number of early investigators. Included were those whose efforts were directed at establishing neuroimmune connections as well as others whose research focused upon the relationship between immunity, cytokines, and behavior. This book brings together outstanding scientists and clinicians who have made major contributions to the rapidly developing eld investigating the relationship between immunity and behavior. The book is divided into three parts. The rst part describes pathways by which the brain and immune systems communicate and int- act with each other. In the chapter “Cytokines and the Blood–Brain Barrier” p- vides insight into interactions between the blood–brain barrier and cytokines. Such interactions underlie basic communication between the immune system and brain that are present in normal as well as in disease conditions. In the chapter “Neu- chemical and Endocrine Responses to Immune Activation: The Role of Cytokines,” the neurochemical and endocrine consequences of immune challenge and cytokine administration on central neurotransmitter activity are discussed.

Introduction To Psychoneuroimmunology

Author : Jorge H. Daruna
ISBN : 9780123820808
Genre : Psychology
File Size : 63. 87 MB
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Health is maintained by the coordinated operation of all the biological systems that make up the individual. The Introduction to Psychoneuroimmunology, Second Edition, presents an overview of what has been discovered by scientists regarding how bodily systems respond to environmental challenges and intercommunicate to sustain health. The book touches on the main findings from the current literature without being overly technical and complex. The result is a comprehensive overview of psychoneuroimmunology, which avoids oversimplification, but does not overwhelm the reader. Single authored for consistency of breadth and depth, with no redundancy of coverage between chapters Covers endocrine-immune modulation, neuro-immune modulation, and the enhancing or inhibiting processes of one or more systems on the others Expanded use of figures, tables, and text boxes

Beyond Mental Illness

Author : David Moyer LCSW
ISBN : 9781493168194
Genre : Psychology
File Size : 30. 40 MB
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Can infections cause Alzheimer's disease, multiple sclerosis, Lou Gherig's Disease and mental illness? Yes, but not just the infections. The body's unique defense against these infections plays a role. This is but one of the startling facts uncovered in Moyer's third book, Beyond Mental Illness. Moyer is a retired licensed clinical social worker with a lifetime of professional experience dealing with mental illness. He has been free to follow the research independent of the cultural limitations that might inhibit other investigators. Moyer's bipolar odyssey began with a novel exploration of factors contributing to his father and son's bipolar disorder. His first book, Too Good to be True? Nutrients Quiet the Unquiet Brain, addressed, among other things, the role of nutrients in treating mental disorders. In Beyond Mental Illness, that odyssey has now morphed into an exploration of factors contributing to mental illness as well as other physical disorders. In this book, Moyer provides a perspective beyond the standard DSM-5 diagnoses and even the very concept of mental illness. The stove-piped diagnoses dominating current medical practices are obsolete. While the medical establishment resists the need for major reformation, the public is beginning to demand science-based diagnoses and treatments. Here Moyer outlines deficiencies in current diagnostic systems that consign many to a lifetime of chronic illness. Their illnesses are not being properly diagnosed and treated. Since the publication of Beyond Mental Illness in 2014, a plethora of academic research in some of the best journals has validated some of his hypotheses. The key for more effective treatments is not to be found in drugs that mitigate downstream biological processes. The key is to identify and treat the diagnosable and treatable upstream biological processes.

The British National Bibliography

Author : Arthur James Wells
ISBN : STANFORD:36105211722678
Genre : English literature
File Size : 23. 59 MB
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Neuroimmune Pharmacology

Author : Tsuneya Ikezu
ISBN : 0387725733
Genre : Medical
File Size : 45. 40 MB
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Neuroimmune pharmacology seeks to harness the immune system to provide pharmacological intervention to combat neurodegenerative diseases. This book provides a comprehensive overview of topics that embrace the link between the immune system and the pathogenesis of neurodegenerative disorders. Results from recent studies strongly suggest that a major part of the process in diseases including Alzheimer’s and Parkinson’s as well as Prion diseases, comes from changes in the innate and adaptive arms of the brain and peripheral immune systems. Thus, the book provides an in-depth study of numerous fields including immunology, pharmacology, neuroscience and neurovirology. It is accompanied by a CD-ROM that includes access to lectures, slide presentations, and question and answers on neuroimmune pharmacology.

Biology Annual Report

Author :
ISBN : UCLA:L0099949448
Genre : Biology
File Size : 82. 65 MB
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Neurobiology Of Mental Illness

Author : Dennis S. Charney
ISBN : 0199857547
Genre : Medical
File Size : 57. 12 MB
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This is a new edition of the first comprehensive text to show how the advances in molecular and cellular biology and in the basic neurosciences have brought the revolution in molecular medicine to the field of psychiatry. The book begins with a review of basic neuroscience and methods for studying neurobiology in human patients then proceeds to discussions of all major psychiatric syndromes with respect to knowledge of their etiology, pathophysiology, and treatment. Emphasis is placed on synthesizing information across numerous levels of analysis, including molecular biology and genetics, cellular physiology, neuroanatomy, neuropharmacology, and behavior, and in translating information from the basic laboratory to the clinical laboratory and finally to clinical treatment. Editors Dennis Charney and Eric Nestle, along with their six section editors and over 150 contributors, have revised and updated all 80 chapters from the previous edition and have added new chapters on topics relating to, for example, genetics, experimental therapeutics, and late-life mood disorders. Both a textbook and a reference book, Neurobiology of Mental Illness is intended for psychiatrists, neuroscientists, and upper level students.

Neuroimmunology Mental Health

Author :
ISBN : UOM:39015032217062
Genre : Nervous system
File Size : 79. 74 MB
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Nih Almanac

Author : National Institutes of Health (U.S.). Division of Public Information
ISBN : STANFORD:36105214597366
Genre : Federal aid to medical care research
File Size : 43. 76 MB
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Author : Antonio L. Teixeira
ISBN : 9780190884468
Genre : Science
File Size : 75. 76 MB
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In recent years, a dedicated effort has been made to understand the immune dysfunction that is associated with major psychiatric disorders. The expanding knowledge of the immune system as a major homeostatic system has been very helpful in indicating new potential biomarkers and therapeutic targets to reduce the burden of psychiatric disorders. Indeed, immune cells, their secreted molecules, and cell signalling events are highly promising. Yet, the literature on immunology of psychiatric disorders is still dispersed, and only a few attempts have been made to consolidate the current knowledge in this expanding area. This book assembles and presents the available data on the immune/inflammatory dysfunction in psychiatric disorders, indicating the potential of immune mechanisms as either biomarkers or therapeutic targets, as well as discussing the challenges ahead of incorporating this knowledge into clinical practice. An international team of senior experts in the field review all psychiatric disorders in order to provide an integrated, in-depth understanding of the role of immune changes in psychiatric diseases for mental health clinicians as well as for researchers in immunology, psychiatry, neurology, and pharmacology.

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