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The Primary Structure Of Transfer Rna

Author : Tat Yana Venkstern
ISBN : 9781468419719
Genre : Science
File Size : 39. 59 MB
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The study of the primary structure of nucleic acids, i. e. , the determination of the nucleotide sequence in ribosomal, transfer, and messenger types of RNA and in DNA, is an essential preliminary to the attempt to correlate the structures of these compounds with their functions. This is one of the most urgent problems in molecular biology, for until it is solved it is im possible to understand fully the mechanisms of fundamental living processes. Research has naturally tended to concentrate on the nucleic acids of smallest molecular weight, namely the transfer RNAs, and tremendous progress has been made in recent years in the unraveling of their structure. In 1958-1959, when structural investigation was still in its infancy, it was even doubted whether the structure of any transfer RNA could be deter mined. No methods of isolating homogeneous preparations were available, and it was uncertain whether the very slight physical and chemical differences between tRNAs of different specificity would be sufficient to allow successful fractionation. When the first enriched preparations were obtained, there arose the problem of whether it was possible to determine the nucleotide sequence having regard to the limited number of heterogeneous structural elements present in tRNA. These doubts were resolved in 1965, when the structure of the first nucleic acid, alanine-specific transfer RNA, was unraveled in Holley's laboratory.

The Primary Structure Of Transfer Rna

Author : Tatʹi︠a︡na Vladimirovna Venkstern
ISBN : 8391009742
Genre : Transfer RNA.
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The Primary Structure Of Transfer Rna

Author : Venkstern T V.
ISBN : 0608145505
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Primary Structure Of Transfer Rna

Author : T. V. Venkstern
ISBN : OCLC:768186242
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File Size : 39. 43 MB
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The Primary Structure Of Transfer Rna

Author : Tatʹi︠a︡na Vladimirovna Venkstern
ISBN : 0396305776
Genre : Transfer RNA.
File Size : 70. 8 MB
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Structure And Function Of Transfer Rna And 5s Rna

Author : Federation of European Biochemical Societies
ISBN : UOM:39015072121380
Genre : RNA
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X Ray Studies On The Three Dimensional Structure Of Transfer Rna

Author : Mindaugas Paul Labanauskas
ISBN : WISC:89010822955
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The Primary Structure Of Euglena Gracilis Cytoplasmic Phenylalanine Transfer Rna

Author : Charles Kasriel Brum
ISBN : OCLC:5861507
Genre : Euglena gracilis
File Size : 39. 16 MB
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Abstract.

Handbook Of Genetics

Author : Robert King
ISBN : 9781461571483
Genre : Medical
File Size : 61. 9 MB
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Many modern geneticists attempt to elucidate the molecular basis of phenotype by utilizing a battery of techniques derived from physical chemistry on subcellular components isolated from various species of organisms. Volume 5 of the Handbook of Genetics provides explanations of the advantages and shortcomings of some of these revolutionary tech niques, and the nonspecialist is alerted to key research papers, reviews, and reference works. Much of the text deals with the structure and func tioning of the molecules bearing genetic information which reside in the nucleus and with the processing of this information by the ribosomes resid ing in the cytoplasm of eukaryotic cells. The mitochondria, which also live in the cytoplasm of the cells of all eukaryotes, now appear to be separate little creatures. These, as Lynn Margulis pointed out in Volume 1, are the colonial posterity of migrant prokaryotes, probably primitive bacteria that swam into the ancestral precursors of all eukaryotic cells and remained as symbionts. They have maintained themselves and their ways ever since, replicating their own DNA and transcribing an RNA quite different from that of their hosts. In a similar manner, the chloroplasts in all plants are self-replicating organelles presumably derived from the blue-green algae, with their own nucleic acids and ribosomes. Four chapters are devoted to the nucleic acids and the ribosomal components of both classes of these semi-independent lodgers. Finally, data from various sources on genetic variants of enzymes are tabulated for ready reference, and an evaluation of this information is attempted.

Informational Biopolymers Of Genes And Gene Expression

Author : R.D. Blake
ISBN : 1891389289
Genre : Science
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This new text examines thebiophysics and biochemistry of nucleic acids and proteins, carving outthe dynamic interface between chemistry and molecular biology, and providing adetailed picture of nucleic acids and proteins, their structures, biologicalproperties, and origins and evolution.

Progress In Biophysics And Molecular Biology

Author : J. A. V. Butler
ISBN : 9781483144412
Genre : Science
File Size : 46. 34 MB
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Progress in Biophysics and Molecular Biology, Volume 32 summarizes the significant progress that has been made in the fields of biophysics and molecular biology. Topics range from metabolic regulation and transfer RNA to cellular metabolism and prokaryotic and eukaryotic ribosomes. This volume consists of five chapters and begins with a discussion of mathematical models used in the study of metabolic regulation, with emphasis on the energy metabolism of eukaryotes. The next chapter examines the possible functions of transfer RNA minor components, paying particular attention to the principle of location-function relationships. The reader is also introduced to spatial-functional correlations in cellular metabolism and highlights the role of organize multienzyme systems, along with the fundamentals of ribosome structure and function in prokaryotes and eukaryotes. A chapter that analyzes the structures and functions of transfer RNA concludes the book. This book will be of interest to scientists, students, and researchers working in the fields of biophysics and molecular biology.

Transfer Rnas And Other Soluble Rnas

Author : Joseph D. Cherayil
ISBN : 0849357446
Genre : Medical
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This fascinating book discusses various methods that have been used from early times to the present for the isolation and characterization of total tRNA, specific tRNAs, and small molecular weight RNAs. Filled with tables and figures, it presents comparative methods and provides an overview of the progress from a historical perspective. The text features chapters on special and recent methods, isolation of tRNA from specific sources, such as chloroplasts and mitochondria, purification, and identification of modified nucleotides. It also covers suppressor tRNAs, aminoacyl tRNA synthetases, and tRNA genes. This volume is an excellent resource for all biological chemists, microbiologists, and researchers.

Structural Rna Synthetic And Unannotated Sequences

Author : Edwin J. Atencio
ISBN : 9781483218847
Genre : Science
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Nucleotide Sequences 1986/1987, Volume VII: Structural RNA, Synthetic, and Unannotated Sequences presents data that reflect the information found in GenBank Release 44.0 of August 1986. This book provides information pertinent to the unique international collaboration between two leading nucleotide sequence data libraries, one based in Europe and one in the United States. Organized into three sections, this volume begins with an overview of the sequences, some basic identifying information, and some of the biological annotations. This text then discusses the EMBL Nucleotide Sequence Data Library, an international center of fundamental research with its main focus in the fields of cell biology, molecular structures, instrumentation, and differentiation. This book discusses as well the GenBank database established in 1982 by the National Institute of General Medical Sciences (NIGMS) of the U.S National Institutes of Health (NIH). This book is a valuable resource for molecular biologists and other investigators collecting the large number of reported DNA and RNA sequences and making them available in computer-readable form.

Nucleic Acids In Plants

Author : Timothy C. Hall
ISBN : 9781351083546
Genre : Science
File Size : 42. 32 MB
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Our ambition in the organization of this book was to explore the current stus of knowledge about nucleic acids in plants. We wanted the reader to be able to learn how this research is being undertaken. Therefore, we asked the contributing authors to include details of approaches and methods. Where feasible, the have provided protocols that can be followed by those who wish to repeat results, extend data, make improvements, or use them in new applications.

Cumulated Index Medicus

Author :
ISBN : OSU:32436001304052
Genre : Medicine
File Size : 62. 32 MB
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The Genetic Mechanism And The Origin Of Life

Author : Lawrence Dillon
ISBN : 9781468424362
Genre : Science
File Size : 24. 99 MB
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As shown in the text, there can be little doubt that the genetic mechanism is, for all practical purposes, equivalent to life itself. Consequently, it is unrealistic to seek knowledge of the origin of life and its subsequent evolution without si multaneously searching for an understanding of how this apparatus arose and evolved. Fortunately, the annual publication over the recent years of thousandS" of papers dealing with the genetic processes has brought the state of knowledge to a level where a synthesis of their major details in relation to life's history is feasible. Because of the voluminous body of literature, no single book can pos sibly treat all the ramifications of this fundamental subject; subdivision into multiple volumes is necessary. This volume, the first of a trilogy, explores the molecular aspects of the problem in connection with the precellular aspects up to the point of the origin of the cell. The second, currently in progress, is con cerned with the subsequent evolution of the cell as revealed by the energy related organelles and their genetic apparatuses and by ultrastructural details of other cellular parts. The third volume, as presently planned, deals with devel opmental, immunological, and other complexities at the organismic level and, in so doing, throws additional light on basic properties of the genetic processes themselves. Thus, the genetic apparatus provides the warp, and evolution the woof, of the intricate fabric that emerges.

Molecular Biophysics

Author : M Volkenstein
ISBN : 9780323144186
Genre : Science
File Size : 57. 55 MB
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Molecular Biophysics presents the fundamental principles of biophysics and their application to the study of the physical properties of biological macromolecules. The merger of biology and physics involves the development of sophisticated instrumentation and the molecular approach to the study of life phenomena. This book is composed of nine chapters and begins with an overview of the thermodynamical aspects and chemical foundations of biophysics. These topics are followed by the physical aspects of macromolecules, with a particular emphasis on the biological functions, conformation, and hydrophobic interactions of proteins. The subsequent chapter describes the structural and electro-optical properties of biopolymers based on X-ray, optical, and spectroscopic analysis. The discussion then shifts to enzymes, their chemical kinetics, catalytic potential, and conformational and cooperative properties. The remaining chapters explore the physical aspects of nucleic acids and the biosynthesis of proteins. This book will prove useful to molecular biophysicists, biologists, physicists, and researchers in the fields of life sciences.

Biochemistry

Author : Debajyoti Das
ISBN : 938059917X
Genre : Biochemistry
File Size : 48. 55 MB
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Dna And Rna Modification Enzymes

Author : Henri Grosjean
ISBN : 9781498713153
Genre : Science
File Size : 86. 38 MB
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This volume is a timely and comprehensive description of the many facets of DNA and RNA modification-editing processes and to some extent repair mechanisms. Each chapter offers fundamental principles as well as up to date information on recent advances in the field (up to end 2008). They ended by a short ‘conclusion and future prospect’ section and an exhaustive list of 35 to up to 257 references (in average 87). Contributors are geneticists, structural enzymologists and molecular biologists working at the forefront of this exciting, fast-moving and diverse field of researches. This book will be a major interest to PhD students and University teachers alike. It will also serve as an invaluable reference tool for new researchers in the field, as well as for specialists of RNA modification enzymes generally not well informed about what is going on in similar processes acting on DNA and vice-versa for specialists of the DNA modification-editing and repair processes usually not much acquainted with what is going on in the RNA maturation field. The book is subdivided into 41 chapters (740 pages). The common links between them are mainly the enzymatic aspects of the different modification-editing and repair machineries: structural, mechanistic, functional and evolutionary aspects. It starts with two general and historical overview of the discovery of modified nucleosides in DNA and RNA and corresponding modification-editing enzymes. Then follows eleven chapters on DNA modification and editing (mechanistic and functional aspects). Two additional chapters cover problems related to DNA/RNA repair and base editing by C-to-U deaminases, followed by three chapters on RNA editing by C-to-U and A-to-I type of deamination. Discussions about interplay between DNA and RNA modifications and the emergence of DNA are covered in two independent chapters, followed by twenty chapters on different but complementary aspects of RNA modification enzymes and their cellular implications. The last chapter concerns the description of the present state-of-the art for incorporating modified nucleosides by in vitro chemical synthesis. At the end of the book, six appendicies give useful details on modified nucleosides, modification-editing enzymes and nucleosides analogs. This information is usually difficult to obtain from current scientific literature.

From Dna To Protein

Author :
ISBN : 9781349162642
Genre :
File Size : 20. 15 MB
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