the target h the penetrator book 1

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Penetration Testing

Author : Georgia Weidman
ISBN : 9781593275952
Genre : Computers
File Size : 50. 39 MB
Format : PDF, Docs
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Penetration testers simulate cyber attacks to find security weaknesses in networks, operating systems, and applications. Information security experts worldwide use penetration techniques to evaluate enterprise defenses. In Penetration Testing, security expert, researcher, and trainer Georgia Weidman introduces you to the core skills and techniques that every pentester needs. Using a virtual machine–based lab that includes Kali Linux and vulnerable operating systems, you’ll run through a series of practical lessons with tools like Wireshark, Nmap, and Burp Suite. As you follow along with the labs and launch attacks, you’ll experience the key stages of an actual assessment—including information gathering, finding exploitable vulnerabilities, gaining access to systems, post exploitation, and more. Learn how to: –Crack passwords and wireless network keys with brute-forcing and wordlists –Test web applications for vulnerabilities –Use the Metasploit Framework to launch exploits and write your own Metasploit modules –Automate social-engineering attacks –Bypass antivirus software –Turn access to one machine into total control of the enterprise in the post exploitation phase You’ll even explore writing your own exploits. Then it’s on to mobile hacking—Weidman’s particular area of research—with her tool, the Smartphone Pentest Framework. With its collection of hands-on lessons that cover key tools and strategies, Penetration Testing is the introduction that every aspiring hacker needs.

Andrews Diseases Of The Skin E Book

Author : William D. James
ISBN : 9780323319690
Genre : Medical
File Size : 47. 79 MB
Format : PDF, Docs
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Effectively diagnose and treat a wide range of skin conditions with the latest edition of the highly regarded Andrews’ Diseases of the Skin: Clinical Dermatology. The 12th edition of this classic reference, by esteemed authors William D. James, MD, Timothy G. Berger, MD, and Dirk M. Elston, MD, provides state-of-the-art information on newly recognized diseases, new conditions, and unusual variants of well-known diseases, as well as new uses for tried-and-true medications and unique drugs for diseases as disparate as melanoma and rosacea. It’s your ideal go-to resource for clinical dermatology, at every stage of your career. Consult this title on your favorite e-reader. Still the only one-volume, go-to dermatology text! Practice with confidence through the valued authorship of seasoned professionals Dr. William D. James, Dr. Timothy G. Berger, and Dr. Dirk M. Elston. Rapidly improve your knowledge of skin conditions through a concise, clinically focused, user-friendly format. Obtain thorough guidance on clinical presentation and therapy for a full range of common and rare skin diseases. Ensure that you’re up to speed with the hottest topics in dermatology, including drug eruptions from new medications, new therapeutics for melanoma, as well as viral infections, biologic agents, and newly described gene targets for treatment. Broaden your knowledge with updated information on serological diagnosis of pemphigus, TNF-I for hidradenitis suppurativa, the use of immunosuppressives for atopic dermatitis, excimer laser for the treatment of vitiligo and much more. Quickly access hundreds of new images depicting a wide variety of skin conditions. Stay up to date with recent society guidelines, including the latest from the American Academy of Dermatology, covering a variety of conditions such as melanoma and atopic dermatitis. Expand your clinical repertoire and meet your patients’ expectations with coverage of the most recent cosmetic agents, their indications, and possible complications.

Ways To Improve Tumor Uptake And Penetration Of Drugs Into Solid Tumors

Author : Fabrizio Marcucci
ISBN : 9782889193509
Genre :
File Size : 83. 86 MB
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The main scope of this topic is to give an update on pharmacologic and non-pharmacologic approaches to enhance uptake and penetration of cancer drugs into tumors. Inadequate accumulation of drugs in tumors has emerged over the last decade as one of the main problems underlying therapeutic failure and drug resistance in the treatment of cancer. Insufficient drug uptake and penetration is causally related to the abnormal tumor architecture. Thus, poor vascularization, increased resistance to blood flow and impaired blood supply represent a first obstacle to the delivery of antitumor drugs to tumor tissue. Decreased or even inverted transvascular pressure gradients compromise convective delivery of drugs. Eventually, an abnormal extracellular matrix offers increased frictional resistance to tumor drug penetration. Abnormal tumor architecture also changes the biology of tumor cells, which contributes to drug resistance through several different mechanisms. The variability in vessel location and structure can make many areas of the tumor hypoxic, which causes the tumor cells to become quiescent and thereby resistant to many antitumor drugs. In addition, the abnormally long distance of part of the tumor cell population from blood vessels provides a challenge to delivering cancer drugs to these cells. We have recently proposed additional mechanisms of tumor drug resistance, which are also related to abnormal tumor architecture. First, increased interstitial fluid pressure can by itself induce drug resistance through the induction of resistance-promoting paracrine factors. Second, the interaction of drug molecules with vessel- proximal tumor cell layers may also induce the release of these factors, which can spread throughout the cancer, and induce drug resistance in tumor cells distant from blood vessels. As can be seen, abnormal tumor architecture, inadequate drug accumulation and tumor drug resistance are tightly linked phenomena, suggesting the need to normalize the tumor architecture, including blood vessels, and/or increase the accumulation of cancer drugs in tumors in order to increase therapeutic effects. Indeed, several classes of drugs (that we refer to as promoter drugs) have been described, that promote tumor uptake and penetration of antitumor drugs, including those that are vasoactive, modify the barrier function of tumor vessels, debulk tumor cells, and overcome intercellular and stromal barriers. In addition, also non-pharmacologic approaches have been described that enhance tumor accumulation of effector drugs (e.g. convection-enhanced delivery, hyperthermia, etc.). Some drugs that have already received regulatory approval (e.g. the anti-VEGF antibody bevacizumab) exert antitumor effects at least in part through normalization of the tumor vasculature and enhancement of the accumulation of effector drugs. Other drugs, acting through different mechanisms of action, are now in clinical development (e.g. NGR-TNF in phase II/III studies) and others are about to enter clinical investigation (e.g. JO-1).

Paperbound Books In Print

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ISBN : UOM:39015085499310
Genre : Bibliography
File Size : 72. 73 MB
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The Publishers Trade List Annual

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ISBN : STANFORD:36105124485777
Genre : United States
File Size : 79. 31 MB
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Pediatric Infectious Diseases E Book

Author : Jeffrey Bergelson
ISBN : 9780323076333
Genre : Medical
File Size : 36. 87 MB
Format : PDF, Mobi
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This new volume in the Requisites in Pediatrics series offers expert advice in the assessment and treatment of infectious diseases in children. An emphasis on common conditions enables you to address the cases you’re most likely to encounter, and discussions of unusual infections helps you determine when to seek additional information or consultation. It delivers all this information designed in a way that compliments your practice and in the proven “high-yield Requisites format—equipping you to master the material quickly. Perfect for quick review, everyday practice, and exam preparation, this is one resource you’ll consult time and time again! Examines infections in terms of their effects on specific body sites or organs to mirror how diagnoses are often made in real practice. Highlights infections in specific patient populations including newborns, transplant patients, travelers, and children with HIV to equip you to address special scenarios. Discusses immunization and basic infection control in doctors’ offices and child-care facilities to reduce the risk of the spread of infections. Presents chapters on fevers of unknown origin and febrile syndromes characterized by rashes to prepare you for difficult-to-diagnose cases. Summarizes basic information and vocabulary concerning microorganisms and antimicrobials essential for the interpretation of laboratory reports. Follows a logical, consistent chapter format to facilitate quick and easy reference. Offers practice-proven guidance on differential diagnoses, lab values / radiologic studies, treatment / therapy recommendations, and advice on when to refer to a specialist. Features a wealth of illustrations and tables that make details clearer, and illuminate important information. Includes highlighted boxes that emphasize relevant case studies • key points of each section • current controversies • and other important topics that can affect your practice.

Management Of Burns An Issue Of Surgical Clinics

Author : Robert Sheridan
ISBN : 9780323320443
Genre : Medical
File Size : 86. 39 MB
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Editor Robert Sheridan and authors review the latest in Management of Burns. Articles will include Reflection: evolution of the field over 50 years, Acute burn procedures and operations, Special injuries and illnesses, Initial evaluation and fluid resuscitation, Critical care of burns, Biology and principles of scar management and burn reconstruction, Management of common post-burn deformities, Burn recovery—physical and emotional rehabilitation, Anesthesia and pain control for burns, Outpatient burn management, Measuring burn outcomes, Burn care in disasters and austere settings, On the horizon--research priorities for the next decade, and more!

Books In Print Supplement

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ISBN : STANFORD:36105210120270
Genre : American literature
File Size : 58. 12 MB
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Antibiotic And Chemotherapy E Book

Author : Roger G. Finch
ISBN : 9780702047657
Genre : Medical
File Size : 40. 14 MB
Format : PDF
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Well-respected and widely regarded as the most comprehensive text in the field, Antibiotic and Chemotherapy, 9th Edition by Drs. Finch, Greenwood, Whitley, and Norrby, provides globally relevant coverage of all types of antimicrobial agents used in human medicine, including all antiviral, antiprotozoan and anthelminthic agents. Comprehensively updated to include new FDA and EMEA regulations, this edition keeps you current with brand-new information about antiretroviral agents and HIV, superficial and mucocutaneous myscoses and systemic infections, management of the immunocompromised patient, treatment of antimicrobial resistance, plus coverage of new anti-sepsis agents and host/microbe modulators. Reference is easy thanks to a unique 3-part structure covering general aspects of treatment; reviews of every agent; and details of treatments of particular infections. Offer the best possible care and information to your patients about the increasing problem of multi-drug resistance and the wide range of new antiviral therapies now available for the treatment of HIV and other viral infections. Stay current with 21 new chapters including the latest information on superficial and mucocutaneous mycoses, systemic infections, anti-retroviral agents, and HIV. Get fresh perspectives and insights thanks to 21 newly-authored and extensively re-written chapters. Easily access information thanks to a unique 3-part structure covering general aspects of treatment; reviews of every agent; and details of treatments of particular infections. Apply the latest treatments for anti-microbial organisms such as MRSA, and multi-drug resistant forms of TB, malaria and gonorrhea. Keep up on the latest FDA and EMEA regulations.

Handbook Of Local Anesthesia E Book

Author : Stanley F. Malamed
ISBN : 9780323242028
Genre : Medical
File Size : 63. 20 MB
Format : PDF, ePub, Docs
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A practical, "how-to" guide to safe anesthesia practices in dentistry, Handbook of Local Anesthesia, 6th Edition covers all the latest advances in science, instrumentation, and pain control techniques. From basic concepts to specific injection techniques, from dosage charts to the proper care and handling of equipment, this book provides in-depth, full-color coverage of key anesthesia topics, including specific hazards and errors in technique that may result in complications. Written by Dr. Stanley Malamed, dentistry's leading expert on this subject, Handbook of Local Anesthesia is a valuable reference that will help you prevent, recognize, and manage complications of local anesthesia administration. Videos on an available companion DVD (sold separately) are narrated by Dr. Stanley Malamed, covering topics such as local anesthetic agents, anesthetic injection techniques, potential complications, and risk management. Full-color photographs and line drawings are included throughout the book. In-depth discussions cover the anesthetic agents used in dentistry, along with their clinical actions. Routes of administration are described for all anesthetics. The proper care and handling of equipment is addressed, along with the problems that may be encountered. Requirements for pain control and local anesthesia within various dental specialties are included. Comprehensive information on Articaine is included, a local anesthetic that is gaining widespread use in the United States. Numerous boxes and tables provide a quick reference and comparison of techniques, drugs, and dosages. Dosage charts, injection techniques, information on duration of action, and contraindications for local anesthetics are included at the end of the book for quick reference. Updated discussions of the armamentarium needed to succeed in local anesthesia delivery reflect the latest available drugs and devices. Updated discussions of the techniques needed to provide successful pain control. Updated step-by-step procedures cover the techniques for administering intraoral anesthesia. The latest advances in science, technology, and pain control techniques are covered.

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